추천 제품
생물학적 소스
bovine
무균
sterile-filtered
제품 라인
BioReagent
양식
solution
농도
10 mg/mL insulin in 25 mM HEPES, pH 8.2
기술
cell culture | mammalian: suitable
single cell analysis: suitable
불순물
endotoxin, tested
pH
7.9-8.5
UniProt 수납 번호
배송 상태
ambient
애플리케이션
Insulin solution from bovine pancreas has been used:
- to study the effect of exogenous insulin on plasma concentrations of glucose, insulin, insulin-like growth factor I (IGF-I), and progesterone (P4) in pubertal beef heifers[1]
- to study the insulin responsiveness of the placenta during pregnancy complications using primary human trophoblast cells and placental villous explants[2]
- to study the effect of insulin receptor signaling dendritic spine density in neonatal mouse hippocampal neurons in vitro[3]
생화학적/생리학적 작용
Insulin is a major glucose-lowering hormone, insufficiency of which causes hyperglycemia observed in type 2 diabetes.[4]
Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.
물리적 형태
stable 2-8 °C
관련 제품
제품 번호
설명
가격
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves
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M M Vick et al.
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Oncotarget, 8(14), 22700-22715 (2017-02-12)
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CENP-F is a large, microtubule-binding protein that regulates multiple cellular processes including chromosome segregation and mitochondrial trafficking at cytokinesis. This multiplicity of functions is mediated through the binding of various partners, like Bub1 at the kinetochore and Miro at mitochondria.
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Scientific reports, 7, 46222-46222 (2017-04-12)
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