L6004

Lincomycin hydrochloride

≥90% (TLC)

• 동의어(들): Epilincomycin, Lincomycin HCL, Lincocin hydrochloride, Methyl 6,8-dideoxy-6-(1-methyl-4-propyl-2-pyrrolidinecarboxamido)-1-thio-D-erythro-α-D-galactooctopyranoside hydrochloride
• 실험식(Hill 표기법): C₁₈H₃₄N₂O₆S · HCl
• CAS Number: 859-18-7
• Molecular Weight: 443.00
• Beilstein: 4171650
• EC Number: 212-726-7
• MDL number: MFCD00083647
• UNSPSC 코드: 51284507
• PubChem Substance ID: 329817633
• NACRES: NA.85

속성

• Quality Level: 200
• 분석: ≥90% (TLC)
• 효능: 800-900 units per mg
• 색상: white to faint yellow
• solubility: H₂O: soluble 50 mg/mL
• 항생제 활성 스펙트럼: Gram-positive bacteria
• 동작 모드: protein synthesis | interferes
• 저장 온도: 2-8°C
• SMILES string: Cl.CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O
• InChI: 1S/C18H34N2O6S.ClH/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25);1H/t9-,10-,11+,12-,13+,14-,15-,16-,18-;/m1./s1
• InChI key: POUMFISTNHIPTI-BOMBIWCESA-N

설명

일반 설명

Chemical structure: macrolide

애플리케이션

Lincomycin hydrochloride is an antibiotic used to study the inhibition of protein synthesis, bacterial antibiotic resistance, and protein and surfactant binding It is produced by Streptomyces lincolnensis var. lincolnensis.

생화학적/생리학적 작용

Mode of action: Lincomycin inhibits bacterial protein synthesis by forming cross-links within the peptidyl transferase loop region of the 23S rRNA.†

Antimicrobial spectrum: Lincomycin hydrochloride is effective against gram-positive bacteria.

제조 메모

This product is soluble in water at 50 mg/mL, yielding a clear, colorless solution.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves