추천 제품
생물학적 소스
soybean
Quality Level
분석
≥96%
양식
powder
작용기
phospholipid
지질 유형
phosphoglycerides
배송 상태
ambient
저장 온도
−20°C
애플리케이션
L-α-Lysophosphatidylinositol sodium salt from Glycine max (soybean) has been used as an agonist of G protein-coupled receptor 55 (GPR55).
생화학적/생리학적 작용
L-α-Lysophosphatidylinositols (LPI) functions as an endogenous ligand for putative cannabinoid receptor and G protein-coupled receptor 55 (GPR55). LPI plays a regulatory role in cell proliferation, migration and function. Increased circulatory levels of LPI has been observed in the obese patients. In addition, overexpression of LPI leads to the development of various types of cancers including ovarian and breast cancer. LPI can be used as a potential diagnostic and prognostic biomarker for ovarian cancer.
L-α-Lysophosphatidylinositols from Glycine max (soybean) are enriched with stearate and palmitate. Soybean Lysophosphatidylinositols may be compared with other lysophosphatidylinositol for biological activities which depend upon the identity of the acylated fatty acid.
품질
Contains primarily palmitic and stearic acids.
제조 메모
Prepared by the action of phospholipase A on L-α-phosphatidylinositol.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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이미 열람한 고객
The L-alpha-lysophosphatidylinositol/GPR55 system and its potential role in human obesity
Moreno-Navarrete J, et al.
Diabetes, 61(2), 281-291 (2012)
The endocannabinoids anandamide and virodhamine modulate the activity of the candidate cannabinoid receptor GPR55
Sharir H, et al.
Journal of Neuroimmune Pharmacology, 7(4), 856-865 (2012)
A role for L-alpha-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells
Ford LA, et al.
British Journal of Pharmacology, 160(3), 762-771 (2010)
A novel biological role for the phospholipid lysophosphatidylinositol in nociceptive sensitization via activation of diverse G-protein signaling pathways in sensory nerves in vivo
Gangadharan V, et al.
Pain, 154(12) (2013)
Lysophosphatidylinositol signalling: New wine from an old bottle.
Pi?eiro R, Falasca M.
Biochimica et Biophysica Acta, 182, 694-705 (2012)
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