M5391

(±)-Metoprolol (+)-tartrate salt

≥98% (titration), powder

• 동의어(들): (±)1-(Isopropylamino)-3-[p-(β-methoxyethyl)phenoxy]-2-propanol (+)-tartrate salt, Lopressor
• Linear Formula: (C₁₅H₂₅NO₃)₂ · C₄H₆O₆
• CAS Number: 56392-17-7
• Molecular Weight: 684.81
• EC Number: 260-148-9
• MDL number: MFCD00056257
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278556
• NACRES: NA.77

속성

• Quality Level: 200
• 분석: ≥98% (titration)
• 양식: powder
• 색상: white to off-white
• solubility: H₂O: 50 mg/mL
• 주관자: Novartis
• SMILES string: O[C@H]([C@@H](O)C(O)=O)C(O)=O.COCCc1ccc(OCC(O)CNC(C)C)cc1.COCCc2ccc(OCC(O)CNC(C)C)cc2
• InChI: 1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/m..1/s1
• InChI key: YGULWPYYGQCFMP-CEAXSRTFSA-N
• 유전자 정보: human ... ADRB1(153)

설명

일반 설명

Metoprolol has antihypertensive and anti-ischemic properties. It is used to treat arrhythmias.

애플리케이션

(±)-Metoprolol (+)-tartrate salt has been used:

• to modulate the immunological parameters in various studies
• to study its effects onCa²⁺-calmodulin-dependent protein kinase II (CaMKII) activity in human and experimental heart failure (HF)
• to examine the contribution of the adrenergic receptors to the production of norepinephrine (NE)-mediated O^2-

생화학적/생리학적 작용

β₁-adrenoceptor antagonist.

특징 및 장점

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

기타 정보

Shelf-life of the powder is at least 4 years.

안전성 정보

• 픽토그램: GHS08,GHS09
• 신호어: Warning
• 유해 및 위험 성명서: H361d,H411
• 예방조치 성명서: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Hazard Classifications: Aquatic Chronic 2 - Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)