L1011
Labetalol hydrochloride
>98% (TLC), powder
동의어(들):
2-Hydroxy-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzamide hydrochloride
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C19H24N2O3 · HCl
CAS Number:
Molecular Weight:
364.87
EC Number:
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77
추천 제품
Quality Level
분석
>98% (TLC)
양식
powder
색상
white
solubility
H2O: soluble
ethanol: soluble
주관자
Schering Plough
SMILES string
Cl.CC(CCc1ccccc1)NCC(O)c2ccc(O)c(c2)C(N)=O
InChI
1S/C19H24N2O3.ClH/c1-13(7-8-14-5-3-2-4-6-14)21-12-18(23)15-9-10-17(22)16(11-15)19(20)24;/h2-6,9-11,13,18,21-23H,7-8,12H2,1H3,(H2,20,24);1H
InChI key
WQVZLXWQESQGIF-UHFFFAOYSA-N
유전자 정보
human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , ADRB1(153) , ADRB2(154) , ADRB3(155)
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생화학적/생리학적 작용
Competitive β-adrenoceptor antagonist.
특징 및 장점
This compound was developed by Schering Plough. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Repr. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
이미 열람한 고객
R Jaboureck-Bouttier et al.
Hypertension in pregnancy, 18(3), 239-247 (1999-12-10)
Increased lipid peroxidation is a putative causal factor for preeclampsia. Because oxygen free radicals are involved in inducing the lipid oxidation chain reaction, we evaluated two beta adrenoreceptor blockers, labetalol and metoprolol, currently used for treating hypertension with regard to
E Riva et al.
British journal of pharmacology, 104(4), 823-828 (1991-12-01)
1. We compared the alpha 1-, alpha 2- and beta 1-adrenoceptor blocking potencies of labetalol with those of its two stereoisomers (RR and SR) in pithed rats and in homogenized rat cerebral cortex and heart. 2. In pithed rats, labetalol
S C Fagan et al.
Experimental neurology, 150(1), 153-158 (1998-03-26)
We examined the relationship between acute hypertension following cerebral embolization and subsequent hemorrhagic transformation (HT) in a rabbit embolic stroke model. We have shown previously that the likelihood and severity of hemorrhage were significantly correlated with the magnitude of an
Cheryl Brandenburg et al.
Frontiers in cellular neuroscience, 14, 577858-577858 (2020-11-27)
Autism spectrum disorder (ASD) is behaviorally defined and diagnosed by delayed and/or impeded language, stereotyped repetitive behaviors, and difficulties with social interactions. Additionally, there are disruptions in motor processing, which includes the intent to execute movements, interrupted/inhibited action chain sequences
Mohamed O Amin et al.
Mikrochimica acta, 186(8), 503-503 (2019-07-05)
The use of carbon black-Fe3O4 magnetic nanocomposite (CB-Fe3O4) as a probe for surface-enhanced laser desorption ionization mass spectrometry (SELDI-MS) with a high extraction efficiency and sensitive detection is described. The magnetic nanocomposite was synthesized and fully characterized using X-ray photoelectron
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