PHR1335

Labetalol Hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

• 동의어(들): Labetalol hydrochloride, 2-Hydroxy-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzamide hydrochloride
• 실험식(Hill 표기법): C₁₉H₂₄N₂O₃ · HCl
• CAS Number: 32780-64-6
• Molecular Weight: 364.87
• EC Number: 251-211-1
• MDL number: MFCD00057663
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329823320
• NACRES: NA.24

속성

• Grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• Agency: traceable to BP L0050000; traceable to USP 1356654
• API family: labetalol
• CofA: current certificate can be downloaded
• 기술: HPLC: suitable; gas chromatography (GC): suitable
• 응용 분야: pharmaceutical (small molecule)
• 형식: neat
• 저장 온도: 2-30°C
• SMILES string: Cl.CC(CCc1ccccc1)NCC(O)c2ccc(O)c(c2)C(N)=O
• InChI: 1S/C19H24N2O3.ClH/c1-13(7-8-14-5-3-2-4-6-14)21-12-18(23)15-9-10-17(22)16(11-15)19(20)24;/h2-6,9-11,13,18,21-23H,7-8,12H2,1H3,(H2,20,24);1H
• InChI key: WQVZLXWQESQGIF-UHFFFAOYSA-N
• 유전자 정보: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , ADRB1(153) , ADRB2(154) , ADRB3(155)

설명

일반 설명

Labetalol Hydrochloride is an adrenergic α-receptor and β-receptor blocking agent, widely used in the treatment of hypertension. It is a sensitive drug and is used quantitatively especially in myocardial infarction and unstable angina, since it decreases blood pressure more rapidly than other beta blockers.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

애플리케이션

Labetalol Hydrochloride may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

분석 메모

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

기타 정보

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

각주

To see an example of a Certificate of Analysis for this material enter LRAA1069 in the slot below. This is an example certificate only and may not be the lot that you receive.

안전성 정보

• 픽토그램: GHS08
• 신호어: Warning
• 유해 및 위험 성명서: H361f
• 예방조치 성명서: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable