콘텐츠로 건너뛰기
Merck
모든 사진(3)

주요 문서

N0665

Sigma-Aldrich

NDSB 211

≥98% (TLC)

동의어(들):

3-[Dimethyl-(2-hydroxyethyl)ammonio]-1-propanesulfonate, Dimethyl(2-hydroxyethyl)(3-sulfopropyl)ammonium hydroxide inner salt, Dimethyl-2-hydroxyethylammoniumpropane sulfonate

로그인조직 및 계약 가격 보기


About This Item

실험식(Hill 표기법):
C7H17NO4S
CAS Number:
Molecular Weight:
211.28
EC Number:
MDL number:
UNSPSC 코드:
12161900
PubChem Substance ID:
NACRES:
NA.25

설명

zwitterionic

Quality Level

분석

≥98% (TLC)

양식

solid

분자량

211.28 g/mol

기술

DNA extraction: suitable

색상

white

solubility

methanol: 5 mg/mL, clear, colorless

SMILES string

OCC[N+](C)(C)CCCS([O-])(=O)=O

InChI

1S/C7H17NO4S/c1-8(2,5-6-9)4-3-7-13(10,11)12/h9H,3-7H2,1-2H3

InChI key

CNXPCGBLGHKAIL-UHFFFAOYSA-N

일반 설명

Dimethyl-2-hydroxyethylammoniumpropane sulfonate, or NDSB 211, is a nondetergent-sulfobetain. It is zwitterionic over a wide pH range, easily removed by dialysis and shows no significant absorption in the near UV range.

애플리케이션

NDSB 211 has been used in a study to assess halophilic protein stabilization by the mild solubilizing agents nondetergent sulfobetaines. It has also been used in a study to investigate an alternative strategy for crystallizing macromolecules.
Non-detergent sulfobetaine is a compound used for non-denaturing protien purification. Increases the extraction yield of membrane, nuclear and cytoskeletal associated proteins. Zwitterionic over a wide pH range, easily removed by dialysis and no significant absorption in the near UV range. Specific applications include microsomal protein extraction, nuclear protein recovery, precipitation reduction in IEF, and membrane-bound protease purification.

기타 정보

This product is non-micelle forming.

픽토그램

Corrosion

신호어

Danger

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Searching for silver bullets: An alternative strategy for crystallizing macromolecules
McPhersona, A., et al.
Journal of Structural Biology, 156, 3887-3406 (2006)
L Vuillard et al.
Analytical biochemistry, 230(2), 290-294 (1995-09-20)
In this work, experiments performed on pig heart and halophilic malate dehydrogenase as well as halophilic elongation factor Tu demonstrate a protein stabilization property from the recently described mild solubilizing agents nondetergent sulfobetaines. A practical application is given by the
Ivanka M Karadzic et al.
Proteomics, 5(2), 354-359 (2005-01-04)
Proteins of haloarchaea are remarkably unstable in low-ionic-strength solvents and tend to aggregate under standard two-dimensional (2-D) gel electrophoresis conditions, causing strong horizontal streaking. We have developed a new approach to generate 2-D maps of halophilic proteins which included washing

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.