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Merck
모든 사진(4)

문서

P2517

Sigma-Aldrich

L-α-Phosphatidylinositol ammonium salt solution from bovine liver

10 mg/mL in chloroform, ≥98% (TLC)

동의어(들):

1,2-Diacyl-sn-glycero-3-phospho-(1-D-myo-inositol), PI, PtdIns

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About This Item

UNSPSC 코드:
12352200
NACRES:
NA.77

Quality Level

분석

≥98% (TLC)

농도

10 mg/mL in chloroform

저장 온도

−20°C

생화학적/생리학적 작용

Phosphatidylinositol is a phosphoglyceride, containing inositol as a cyclohexanol head group. The phosphatidylinositol signaling pathway is also called as double signaling pathway as it generates two secondary messengers. It is associated with a number of physiological processes in plants. This includes the development of pollen and vascular organs, root and root hair growth, hormone response and stress tolerance.
Phospholipid membrane component, precursor of inositol phosphates.

특징 및 장점

This compound is featured on the Phosphoinositide Kinases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

기타 정보

Contains primarily stearic and arachidonic acids.

픽토그램

Skull and crossbonesHealth hazard

신호어

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

표적 기관

Central nervous system, Liver,Kidney

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


시험 성적서(COA)

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문서 라이브러리 방문

Cell Biology, 471-471 (2007)
Sarah J Tilley et al.
Structure (London, England : 1993), 12(2), 317-326 (2004-02-14)
Phosphatidylinositol transfer protein alpha (PITPalpha) selectively transports and promotes exchange of phosphatidylinositol (PI) and phosphatidylcholine (PC) between lipid bilayers. In higher eukaryotes PITPalpha is required for cellular functions such as phospholipase C-mediated signaling, regulated exocytosis, and secretory vesicle formation. We
Functional Characterization of Arabidopsis Phosphatidylinositol Monophosphate 5-kinase 2 in Lateral Root Development, Gravitropism and Salt Tolerance, 2-2 (2014)
S J Heydrick et al.
The Journal of clinical investigation, 91(4), 1358-1366 (1993-04-01)
Activation of phosphatidylinositol-3-kinase (PI3K) is one of the earliest postreceptor events in the insulin signaling pathway. Incubation of soleus muscles from lean mice with 50 nM insulin caused a 3-10-fold increase in antiphosphotyrosine-immunoprecipitable PI3K (antiPTyr-PI3K) activity within 2 min in
D Voelker et al.
Biophysical journal, 70(2), 818-830 (1996-02-01)
We have measured the distribution of the hexavalent ruthenium red cation (RuR) between water and phospholipid membranes, have shown the critical importance of membrane negative surface charge for RuR binding, and determined the association constant of RuR for different phospholipid

문서

지질 신호전달 연구를 위한 생체 활성 저분자

Discover Bioactive Small Molecules for Lipid Signaling Research

프로토콜

(soybean), ≥97%; L-α-Phosphatidylethanolamine from egg yolk, Type III, ≥97% (TLC), lyophilized powder; L-α-Phosphatidylcholine, from egg yolk, Type XVI-E, ≥99% (TLC), lyophilized powder; Sphingomyelin, from chicken egg yolk, ≥95%

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