추천 제품
분석
≥98%
Quality Level
양식
powder
mp
183-184 °C (lit.)
저장 온도
2-8°C
SMILES string
COc1cc(cc(OC)c1OC)[C@H]2C3C(COC3=O)[C@@H](O)c4cc5OCOc5cc24
InChI
1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1
InChI key
YJGVMLPVUAXIQN-XVVDYKMHSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
애플리케이션
Podophyllotoxin has been used as a reference compound for evaluating the cytotoxicity in VERO cells. It has also been used as a reference standard in high-performance liquid chromatography (HPLC).
생화학적/생리학적 작용
Inhibits microtubule assembly; antineoplastic.
Podophyllotoxin is a naturally occurring lignan obtained from resin podophyllin present in the genus Podophyllum. It exhibits antiviral and antimitotic properties. Podophyllotoxin may be used to treat anogenital warts in children and dermatological conditions caused by psoriasis vulgaris. It may also be used as a therapeutic agent to treat genital tumors, Wilms tumors, lung cancer, and lymphomas.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
이미 열람한 고객
Diterpenoids as potential anti-malarial compounds from Andrographis paniculata
Dwivedi M, et al.
Beni-Suef University Journal of Basic and Applied Sciences, 10(1), 1-16 (2021)
Podophyllotoxin: current perspectives
Qian L, et al.
Current Bioactive Compounds, 3(1), 37-66 (2007)
Manish Kumar Dwivedi et al.
Journal of ethnopharmacology, 275, 114076-114076 (2021-04-01)
Limited drugs, rise in drug resistance against frontline anti-malarial drugs, non-availability of efficacious vaccines and high cost of drug development hinders malaria intervention programs. Search for safe, effective and affordable plant based anti-malarial agents, thus becomes crucial and vital in
High-elevation cultivation increases anti-cancer podophyllotoxin accumulation in Podophyllum hexandrum
Li M, et al.
Industrial Crops and Products, 121, 33-344 (2018)
Ronald W Brown et al.
RSC medicinal chemistry, 11(12), 1413-1422 (2021-06-08)
African sleeping sickness is a potentially fatal neglected disease affecting sub-Saharan Africa. High-throughput screening identified the thiazolyl-benzothiophenamide 1 to be active against the causative parasite, Trypanosoma brucei. This work establishes structure-activity relationships of 1, guiding the design of second generation
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.