추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
lyophilized powder
종 반응성
human, mouse, rat
기술
immunohistochemistry: suitable using mouse brain sections
western blot: 1:200 using rat brain membranes or human platelets
UniProt 수납 번호
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... P2RY12(64805)
mouse ... P2ry12(70839)
rat ... P2ry12(64803)
일반 설명
Purinergic receptor or platelet adenosine 5′-diphosphate (ADP) receptor P2Y12 is a G-protein-coupled receptor. The gene encoding it is localized on human chromosome 3q25.1.
면역원
peptide corresponding to amino acid residues 125-142 of human P2Y12. This epitope is highly homologous in rat and mouse (16/18 residues identical).
애플리케이션
Anti-Purinergic Receptor P2Y12 antibody produced in rabbit has been used in Western blotting.
생화학적/생리학적 작용
Purinergic receptor or platelet adenosine 5′-diphosphate (ADP) receptor P2Y12 has a role in platelet aggregation induced by ADP. Dysfunctional mutations in the protein have been linked with bleeding disorders. Studies have indicated that mice deficient in the P2Y12 receptor show decreased tumor metastasis.
물리적 형태
Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.05% sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Inherited dysfunctional platelet P2Y12 receptor mutations associated with bleeding disorders.
Lecchi A
Hamostaseologie (2016)
Competitive mode and site of interaction of ticagrelor at the human platelet P2Y12-receptor
K. Hoffman
Journal of Thrombosis and Haemostasis (2014)
Supplementary Table 1. Sample demographics for participants included in genome-wide association analyses
Hypertension (2016)
Leukotriene E4 induces MUC5AC release from human airway epithelial NCI-H292 cells
Hideaki Shirasaki
Allergology International (2014)
Expression and Localization of Purinergic P2Y12 Receptor in Human Nasal Mucosa
Hideaki Shirasaki
Allergology International (2013)
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