PRS2325

Anti-CASPASE-12 (ab1) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 동의어(들): Anti-Casp-12
• MDL number: MFCD03454856
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: predicted mol wt 46 kDa
• 종 반응성: rat, mouse, human
• 기술: immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• UniProt 수납 번호: O08736
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: mouse ... Casp12(12364)

설명

일반 설명

Caspase 12 (CASP12), a member of the caspase family, is expressed in the Golgi complex.

면역원

a peptide corresponding to amino acids 2-17 of murine caspase-12.

애플리케이션

Anti-CASPASE-12 (ab1) antibody produced in rabbit has been used in western blotting.

생화학적/생리학적 작용

Murine caspase 12 (CASP12) is activated during endoplasmic reticulum stress and activates other caspases which act on substrates, ultimately leading to apoptosis. The protein has been shown to be activated during progression of retinal degeneration in animal models. In mice models, CASP12 has been shown to cause neuronal death resulting from ischemia/reperfusion.

결합

The action of this antibody can be blocked using blocking peptide SBP2325.

물리적 형태

Solution in phosphate buffered saline containing 0.02% sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable