추천 제품
생물학적 소스
synthetic (organic)
Quality Level
분석
≥98% (HPLC)
양식
powder
색상
white
solubility
DMSO: ~18 mg/mL
주관자
Sanofi Aventis
저장 온도
2-8°C
SMILES string
O=C(N1[C@](CCC2)([H])[C@]2([H])C[C@H]1C(O)=O)[C@H](C)N[C@H](C(OCC)=O)CCC3=CC=CC=C3
InChI
1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m0/s1
InChI key
HDACQVRGBOVJII-JBDAPHQKSA-N
유전자 정보
human ... ACE(1636)
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생화학적/생리학적 작용
Angiotensin converting enzyme (ACE) inhibitor.
특징 및 장점
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Repr. 1B
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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시험 성적서(COA)
이미 열람한 고객
JAMA internal medicine, 173(18), 1682-1692 (2013-08-14)
Type 2 diabetes mellitus and associated chronic kidney disease (CKD) have become major public health problems. Little is known about the influence of diet on the incidence or progression of CKD among individuals with type 2 diabetes. To examine the
Pharmacogenetics and genomics, 23(9), 470-478 (2013-07-11)
The objective of this study was to identify genetic variants associated with angiotensin-converting enzyme (ACE) inhibitor-associated angioedema. We carried out a genome-wide association study in 175 individuals with ACE inhibitor-associated angioedema and 489 ACE inhibitor-exposed controls from Nashville (Tennessee) and
American journal of physiology. Renal physiology, 304(6), F808-F819 (2012-11-09)
Bardoxolone methyl is an antioxidant inflammation modulator acting through induction of Keap1-Nrf2 pathway. Results from a recent phase IIb clinical trial reported that bardoxolone methyl was associated with improvement in the estimated glomerular filtration rate in patients with advanced chronic
Clinical journal of the American Society of Nephrology : CJASN, 8(2), 233-240 (2012-11-28)
The microvascular circulation plays an important role in bone health. This study examines whether albuminuria, a marker of renal microvascular disease, is associated with incident hip and pelvic fractures. This study reanalyzed data from the Ongoing Telmisartan Alone and in
American journal of nephrology, 37(1), 65-73 (2013-01-19)
Diabetic nephropathy is the main cause of end-stage renal disease. N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP), a physiological tetrapeptide hydrolyzed by the angiotensin-converting enzyme (ACE), has antifibrotic effects in the cardiovascular system and in the kidney in experimental models of hypertension, heart failure and
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