S1450
Anti-Superoxide Dismutase (MnSOD) (DD-17)−Cy3 antibody produced in rabbit
1-2 mg/mL, affinity isolated antibody, buffered aqueous solution
동의어(들):
Anti-IPO-B, Anti-Indophenoloxidase B, Anti-MNSOD, Anti-Manganese Superoxide Dismutase 2, Anti-Manganese dependent SOD, Anti-Mitochondrial SOD, Anti-SOD2, Anti-Superoxide dismutase 2
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모든 사진(3)
About This Item
UNSPSC 코드:
12352203
NACRES:
NA.43
추천 제품
생물학적 소스
rabbit
Quality Level
결합
CY3 conjugate
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
종 반응성
human, rat, mouse
포장
antibody small pack of 25 μL
농도
1-2 mg/mL
기술
direct immunofluorescence: 2-5 μg/mL using human HeLa, rat NRK and mouse 3T3 cells.
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... SOD2(6648)
일반 설명
The SOD2 (superoxide dismutase 2) gene is mapped to human chromosome 6q25.3. The encoded protein functions as a tetramer and is localized to mitochondria.
면역원
synthetic peptide corresponding to amino acid residues 183-199 of human superoxide dismutase (MnSOD), conjugated to KLH. The corresponding sequence is conserved in many eukaryotes.
애플리케이션
Anti-Superoxide Dismutase (MnSOD) (DD-17)-Cy3 antibody produced in rabbit has been used in immunohistochemistry.
생화학적/생리학적 작용
Superoxide dismutase 2 (SOD2) is an antioxidant enzyme and catalyzes the conversion of superoxide to hydrogen peroxide and molecular oxygen. The enzyme offers protection against oxidative damage induced by reactive oxygen species and is also radioprotective. The gene is associated with the metastasis and invasion process of salivary adenoid cystic carcinoma. Manganese SOD is involved in detoxification.
물리적 형태
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Patrick D Bhola et al.
The Journal of clinical investigation, 126(10), 3827-3836 (2016-09-07)
Upfront resistance to chemotherapy and relapse following remission are critical problems in leukemia that are generally attributed to subpopulations of chemoresistant tumor cells. There are, however, limited means for prospectively identifying these subpopulations, which hinders an understanding of therapeutic resistance.
Radiation-induced SOD2 overexpression sensitizes colorectal cancer to radiation while protecting normal tissue.
Zhang Z, et al.
Oncotarget, 8(5), 7791-7791 (2017)
SOD2 deregulation enhances migration, invasion and has poor prognosis in salivary adenoid cystic carcinoma.
Chang B, et al.
Scientific Reports, 6, 25918-25918 (2016)
Two functional variants of the superoxide dismutase genes in Finnish families with asthma.
Kinnula V L, et al.
Thorax, 59(2), 116-119 (2004)
Substrate-analog binding and electrostatic surfaces of human manganese superoxide dismutase.
Azadmanesh J, et al.
Journal of Structural Biology, 199(1), 68-75 (2017)
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