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Merck
모든 사진(2)

주요 문서

S4762

Sigma-Aldrich

Streptavidin from Streptomyces avidinii

essentially salt-free, lyophilized powder, ≥13 units/mg protein

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About This Item

CAS Number:
MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.46

양식

essentially salt-free, lyophilized powder

Quality Level

특이 활성도

≥13 units/mg protein

분자량

~60 kDa

용량

4 mol/mol (Biotin)

응용 분야

research pathology

저장 온도

−20°C

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일반 설명

Streptavidin derives its name from its bacterial source Streptomyces avidinii and from the hen egg-white protein, avidin, which has high affinity to biotin. Its homologous core shares 33% sequence similarity with avidin, as well as sharing a common tetrameric structure. It is a crystalline tetrameric protein, with a molecular weight of 4*15000Da. It binds four molecules of biotin. Streptavidin lacks carbohydrate and sulfur-containing amino acids.
Streptavidin is a crystalline protein isolated from the bacterium Streptomyces avidinii and possesses biotin-binding ability. It has four binding sites for biotin like avidin and binds four molecules of biotin. Streptavidin is now considered as a new type of biotin-binding protein.

애플리케이션

Streptavidin from Streptomyces avidinii has been used:
  • in wire functionalization
  • in streptavidin capture enzyme-linked immunosorbent assay (ELISA)
  • in microbubble preparation

제조 메모

Affinity purified.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

A rapid streptavidin-capture ELISA specific for the detection of antibodies to feline foamy virus.
Winkler IG et al
Journal of Immunological Methods, 207(1), 69-77 (1997)
Mapping of functional domains in the p22(phox) subunit of flavocytochrome b(559) participating in the assembly of the NADPH oxidase complex by "peptide walking".
Dahan I et al
The Journal of Biological Chemistry, 277(10), 8421-8432 (2002)
Timo Vögtle et al.
eLife, 8 (2019-08-23)
The immunoreceptor tyrosine-based inhibition motif (ITIM)-containing receptor G6b-B is critical for platelet production and activation. Loss of G6b-B results in severe macrothrombocytopenia, myelofibrosis and aberrant platelet function in mice and humans. Using a combination of immunohistochemistry, affinity chromatography and proteomics
Zhihong Shen et al.
Analytical chemistry, 77(3), 797-805 (2005-02-01)
In this paper, we describe a novel nonlabeled biosensor with high diagnostic potential for rapid and sensitive detection of antigens in complex biological samples. The biosensor comprises a piezoimmunosensor (PZ) displaying a specially constructed recombinant antibody on its surface. The
Evaluation of a microwire sensor functionalized to detect Escherichia coli bacterial cells
Lu L and Jun S
Biosensors And Bioelectronics, 36(1), 257-261 (2012)

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