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Merck
모든 사진(3)

주요 문서

S6635

Sigma-Aldrich

Span® 20

greener alternative

동의어(들):

Sorbitan laurate, Sorbitan monolaurate

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC 코드:
12161900
PubChem Substance ID:
NACRES:
NA.25

설명

non-ionic

Quality Level

분자량

346.47 g/mol

환경친화적 대안 제품 특성

Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

농도

≥44% (GC)

환경친화적 대안 카테고리

SMILES string

CCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O

InChI

1S/C18H34O6/c1-2-3-4-5-6-7-8-9-10-11-16(21)23-13-15(20)18-17(22)14(19)12-24-18/h14-15,17-20,22H,2-13H2,1H3/t14-,15?,17+,18+/m0/s1

InChI key

LWZFANDGMFTDAV-WYDSMHRWSA-N

일반 설명

Span 20 is a co-surfactant.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is 100% bio-based non-ionic surfactant, thus aligns with "Use of Renewable Feedstocks" and belongs to "12 principles aligned" category of our greener alternatives.

애플리케이션

Span 20 has been used in a study to assess enhanced solubility and oral bioavailability of itraconazole. It has also been used in a study to investigate the oxidation of unsaturated lipids in oil-in-water emulsions.

기타 정보

Fatty acid composition: Lauric acid (C12:0) ≥ 44%; balance primarily myristic (C14:0), palmitic (C16:0) and linolenic (C18:3) acids.

법적 정보

Span is a registered trademark of Croda International PLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

>300.2 °F - closed cup

Flash Point (°C)

> 149 °C - closed cup

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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이미 열람한 고객

Claire Berton et al.
Journal of colloid and interface science, 377(1), 244-250 (2012-04-25)
The development of lipid oxidation in oil-in-water (O/W) emulsions is widely influenced by the properties of the interfacial layer, which separates the oil and water phases. In this work, the effect of the structure of the interface on the oxidative
Muhammad Moniruzzaman et al.
Journal of colloid and interface science, 352(1), 136-142 (2010-09-10)
In this paper, we report a novel ionic liquid-in-oil (IL/o) microemulsion which is able to dissolve pharmaceuticals that are insoluble or sparingly soluble in water and most of pharmaceutical grade organic liquids. Towards this approach, the nanometer-sized ionic liquid droplets
Yung-Chih Kuo et al.
Colloids and surfaces. B, Biointerfaces, 76(1), 286-291 (2009-12-17)
This study analyzes the effects of Tween 80 and Span 20 on the electrical interaction between cationic solid lipid nanoparticles (CSLNs) and human brain microvascular endothelial cells (HBMECs). Electrophoretic mobility, zeta potential and fixed charge density of CSLNs and HBMECs
Swati De et al.
Journal of colloid and interface science, 386(1), 9-15 (2012-08-25)
This work outlines a novel method for the synthesis of stable gold nanoparticles within the spatially confined region of vesicles. For the first time, Span/cholesterol based niosomes have been used for nanoparticle synthesis. The restricted geometry within niosomes prevents nanoparticle
Pankaj Karande et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 31(1), 1-7 (2007-03-21)
Certain mixtures of chemicals are known to synergistically enhance skin permeability to drugs. Here, we report on the transport enhancing properties of mixtures of an anionic surfactant, sodium lauroylsarcosinate (NLS) and a non-ionic surfactant, sorbitan monolaurate (S20) in 1:1 phosphate

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