추천 제품
생물학적 소스
mouse
Quality Level
결합
peroxidase conjugate
항체 형태
purified from hybridoma cell culture
항체 생산 유형
primary antibodies
클론
9E10, monoclonal
양식
lyophilized powder
종 반응성
human
포장
vial of 100 μL
농도
~2 mg/mL
기술
immunoblotting: 1:250-1:500 using lysate of HEK-293T cells over expressing c-Myc fusion protein
immunohistochemistry: suitable
동형
IgG1
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... MYC(4609)
일반 설명
Monoclonal Anti-c-Myc (mouse IgG1 isotype) is derived from the 9E10 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with synthetic peptide of the human p62c-myc protein, conjugated to KLH. c-Myc is a proto-oncogene localized on long arm of human chromosome 8. The encoded protein contains an N-terminal transactivation domain. The human c-Myc proto-oncogene is the cellular homolog of the avian v-Myc gene found in several leukemogenic retroviruses.
특이성
Monoclonal Anti-Calponin specifically recognizes smooth muscle Calponin.
면역원
Synthetic peptide of the human p62c-myc protein.
애플리케이션
Anti-c-Myc-Peroxidase antibody, Mouse monoclonal may be used in immunoblotting and immunohistology.
생화학적/생리학적 작용
c-Myc is a transcription factor involved in regulation of cell growth, proliferation, differentiation and apoptosis. It is implicated in DNA replication, RNA splicing or transcription. Increased expression of the gene is associated with the development of various types of human cancers.
물리적 형태
Supplied as lyophilized powder. After reconstitution with 0.1 mL of distilled water to a final antibody concentration of ∼ 2 mg/mL, the solution contains 1% BSA, 2.5% trehalose, 0.05% MIT in 0.01 M sodium phosphate buffered saline
저장 및 안정성
Store the lyophilized product at 2–8 °C. For extended storage after reconstitution, keep at –20 °C in working aliquots. Avoid repeated freeze-thaw cycles. For continuous use after reconstitution, keep at 2–8 °C for up to 1 month. Solutions at working dilution should be discarded if not used within 12 hours.
면책조항
Unless otherwise stated in our catalog, our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Skin Sens. 1
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
The c-Myc target gene network
Dang CV, et al.
Seminars in Cancer Biology, 16(4), 253-264 (2006)
Prognostic Value of c-Myc Immunohistochemical Expression in Muscle Invasive Urothelial Carcinoma of the Urinary Bladder: A Retrospective Study
Elwy AE, et al.
Asian Pacific Journal of Cancer Prevention, 20(12), 3735-3735 (2019)
Lin Zhu et al.
eLife, 12 (2024-01-29)
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Journal of virology, 96(12), e0041222-e0041222 (2022-06-03)
SARS-CoV-2 is the causative agent of the ongoing pandemic of coronavirus disease 2019 (COVID-19) and poses a significant threat to global health. N protein (NP), which is a major pathogenic protein among betacoronaviruses, binds to the viral RNA genome to
Tong Zheng et al.
Journal of virology, 98(4), e0156523-e0156523 (2024-03-06)
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed a worldwide threat in the past 3 years. Although it has been widely and intensively investigated, the mechanism underlying the coronavirus-host interaction requires further elucidation, which
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