SAB4500974
Anti-Fibronectin Antibody
rabbit polyclonal
동의어(들):
CIG, FINC, cold-insoluble globulin, fibronectin, fibronectin 1
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모든 사진(2)
About This Item
UNSPSC 코드:
12352203
NACRES:
NA.41
결합:
unconjugated
application:
ELISA
IHC
WB
IHC
WB
클론:
polyclonal
종 반응성:
rat, mouse, human
citations:
19
기술:
ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
추천 제품
제품명
Anti-Fibronectin 1 antibody produced in rabbit, affinity isolated antibody
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
antigen 262 kDa
종 반응성
rat, mouse, human
농도
~1 mg/mL
기술
ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... FN1(2335)
일반 설명
Anti-Fibronectin 1 antibody detects endogenous levels of total Fibronectin 1 protein.
Fibronectin 1 is a glycoprotein of the extracellular matrix that is coded by FN1 gene. It is expressed in the plasma and at the cell surface. It is mapped to human chromosome 2q35.
면역원
The antiserum was produced against synthesized peptide derived from human Fibronectin 1.
Immunogen Range: 2337-2386
Immunogen Range: 2337-2386
애플리케이션
Anti-Fibronectin 1, C-Terminal antibody has been used in western blotting, cell staining and immunofluorescence.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
생화학적/생리학적 작용
Fibronectin participates in cell adhesion, growth, migration, wound healing, blood coagulation and metastasis. Mutations in FN1 results in glomerulopathy. It plays an important role in cell attachment and spreading, control of cell cytoskeleton, morphology and differentiation. FN1 is also involved in extracellular matrix formation, hemostasis and thrombosis.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
이미 열람한 고객
Kusuma Suphakhong et al.
The Journal of biological chemistry, 298(11), 102554-102554 (2022-10-03)
N6-methyladenosine (m6A) is the most common internal chemical modification of mRNAs involved in many pathological processes including various cancers. In this study, we investigated the m6A-dependent regulation of JUN and JUNB transcription factors (TFs) during transforming growth factor-beta-induced epithelial-mesenchymal transition
Colorectal Cancer Aggressiveness is Related to Fibronectin Over Expression, Driving the Activation of SDF-1:CXC
Fernandes SG, et al.
International Journal of Cancer and Clinical Research, 3(8), 72-81 (2016)
Jiangtao Yu et al.
Journal of experimental & clinical cancer research : CR, 37(1), 222-222 (2018-09-12)
Emerging evidence has shown long noncoding RNAs (lncRNAs) exert important roles in colorectal cancer (CRC) tumorigenesis. However, most lncRNAs involved in this process remain undefined and the underlying molecular mechanisms mediated by lncRNAs are largely unknown. An unbiased screening was
Minoru Terashima et al.
The Journal of biological chemistry, 293(47), 18016-18030 (2018-09-29)
Long noncoding RNAs (lncRNAs) are important regulatory molecules in various biological and pathological processes, including cancer development. We have previously shown that the MEG3 lncRNA plays an essential role in transforming growth factor-β (TGF-β)-induced epithelial-mesenchymal transition (EMT) of human lung
Ziying Jian et al.
Cellular and molecular gastroenterology and hepatology, 6(4), 429-449 (2018-09-28)
Although nearly half of pancreatic ductal adenocarcinoma (PDAC) patients have diabetes mellitus with episodes of hyperglycemia, its tumor microenvironment is hypoglycemic. Thus, it is crucial for PDAC cells to develop adaptive mechanisms dealing with oscillating glucose levels. So far, the
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