추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
분자량
antigen 76 kDa
종 반응성
rat, mouse, human
농도
~1 mg/mL
기술
ELISA: 1:40000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
phosphorylation (pThr497)
유전자 정보
human ... PRKCA(5578) , PRKCB(5579) , PRKCD(5580) , PRKCE(5581) , PRKCG(5582) , PRKCH(5583) , PRKCQ(5588) , PRKCZ(5590)
일반 설명
Protein kinase C is a member of the cAMP-dependent, cGMP-dependent, and protein kinase C (AGC) superfamily of protein kinases. It has more than14 isoforms. A catalytic domain with an ATP binding site and a substrate-binding site is found in all PKC isoforms.
면역원
The antiserum was produced against synthesized peptide derived from human PKC-pan around the phosphorylation site of Thr497.
Immunogen Range: 623-672
Immunogen Range: 623-672
애플리케이션
Anti-phospho-PKC-pan (pThr497) antibody produced in rabbit has been used in western blot analysis (1:500).
생화학적/생리학적 작용
Protein kinase Cs (PKCs) are involved in the growth and function of the gastrointestinal tract and the immune response. PKCs regulates cyclins, cyclin-dependent kinases (cdks), cdk inhibitors, and cell division cycle 25 (cdc25) phosphatases.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Genevieve L Wojcik et al.
mBio, 11(1) (2020-02-06)
Diarrhea is a major cause of both morbidity and mortality worldwide, especially among young children. Cryptosporidiosis is a leading cause of diarrhea in children, particularly in South Asia and sub-Saharan Africa, where it is responsible for over 200,000 deaths per
Adrian R Black et al.
Frontiers in immunology, 3, 423-423 (2013-01-22)
A link between T cell proliferation and the protein kinase C (PKC) family of serine/threonine kinases has been recognized for about 30 years. However, despite the wealth of information on PKC-mediated control of, T cell activation, understanding of the effects
Serine and threonine phosphorylation
Plattner F and Bibb JA
Basic Neurochemistry, 467-492 (2012)
Shujie Ning et al.
International journal of molecular sciences, 20(7) (2019-04-17)
Previous studies have demonstrated that monochromatic light affects plasma melatonin (MEL) levels, which in turn regulates hepatic insulin-like growth factor I (IGF-I) secretion via the Mel1c receptor. However, the intracellular signaling pathway initiated by Mel1c remains unclear. In this study
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