SAB5701788

Anti-Phospho-eIF2α-S51 antibody produced in rabbit

• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 생산 유형: primary antibodies
• 클론: monoclonal
• 양식: liquid
• 종 반응성: human, mouse, rat
• 농도: 1.5 mg/mL
• 기술: western blot: 1:500-1:2000
• UniProt 수납 번호: P05198
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pSer51)
• 유전자 정보: human ... EIF2S1(1965)

설명

일반 설명

The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]

면역원

A synthesized peptide derived from human Phospho-EIF2S1 (S51).

물리적 형태

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable