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Merck
모든 사진(1)

문서

SML0868

Sigma-Aldrich

Purmorphamine

≥98% (HPLC), powder, Hedgehog signaling activator

동의어(들):

2-(1-Naphthoxy)-6-(4-morpholinoanilino)-9-cyclohexylpurine; 9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-

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About This Item

실험식(Hill 표기법):
C31H32N6O2
CAS Number:
Molecular Weight:
520.62
UNSPSC 코드:
51111800
NACRES:
NA.77

product name

Purmorphamine, ≥98% (HPLC)

분석

≥98% (HPLC)

형태

powder

색상

white to beige

solubility

DMSO: 5 mg/mL, clear (warmed)

저장 온도

−20°C

InChI

1S/C31H32N6O2/c1-2-9-25(10-3-1)37-21-32-28-29(33-23-13-15-24(16-14-23)36-17-19-38-20-18-36)34-31(35-30(28)37)39-27-12-6-8-22-7-4-5-11-26(22)27/h4-8,11-16,21,25H,1-3,9-10,17-20H2,(H,33,34,35)

InChI key

FYBHCRQFSFYWPY-UHFFFAOYSA-N

애플리케이션

Purmorphamine has been used to study the consequences of upregulation of Hedgehog signalling pathway in Tupfel long fin strain Zebrafish.

생화학적/생리학적 작용

Purmorphamine activates the Hedgehog (Hh) signaling pathway, directly binding to the Smoothened (Smo) receptor. In various studies, purmorphamine has been shown to induce osteoblast differentiation, generate cardiomyocytes from human embryonic stem cells, increase the neuronal differentiation of a human striatal neural stem cell line, and to differentiate human umbilical cord mesenchymal stem cells (hUCMSCs) into motoneurons.

픽토그램

Health hazard

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Muta. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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