SML1103

Entecavir

≥98% (HPLC)

• 동의어(들): 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one, 2-Amino-9-[(1S,3R,4S)-4-hydroxy-3-hydroxymethyl-2-methylene-cyclopentyl]-3,9-dihydro-purin-6-one, BMS 200475, SQ 34,676
• 실험식(Hill 표기법): C₁₂H₁₅N₅O₃
• CAS Number: 142217-69-4
• Molecular Weight: 277.28
• MDL number: MFCD11046562
• UNSPSC 코드: 51111800
• PubChem Substance ID: 329825478
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 광학 활성: [α]/D +25 to +40°, c = 0.2 in H₂O
• 저장 조건: desiccated
• 색상: white to beige
• solubility: H₂O: 0.5 mg/mL, clear (warmed)
• 저장 온도: −20°C
• SMILES string: O=C1C2=C(N([C@H]3C[C@H](O)[C@@H](CO)C3=C)C=N2)NC(N)=N1
• InChI: 1S/C12H15N5O3/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20)/t6-,7-,8-/m0/s1
• InChI key: QDGZDCVAUDNJFG-FXQIFTODSA-N

설명

생화학적/생리학적 작용

Entecavir is an antiviral guanine analog that inhibits reverse transcription, DNA replication and transcription in the viral replication process. Entecavir is used to treat hepatitis B.

Entecavir is an antiviral guanine analog that inhibits reverse transcription, DNA replication and transcription.

Entecavir is used as an effective drug to treat lamivudine-refractory patients with chronic hepatitis B virus (CHB) at a dose of 1 mg daily.

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H351
• 예방조치 성명서: P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable