SML1900

Sobetirome

≥98% (HPLC)

• 동의어(들): 2-[4-[[4-Hydroxy-3-(1-methylethyl)phenyl]methyl]-3,5-dimethylphenoxy]acetic acid, 3,5-Dimethyl-4-(4′-hydroxy-3′-isopropylbenzyl)phenoxyacetic acid, GC 1, GC-1
• 실험식(Hill 표기법): C₂₀H₂₄O₄
• CAS Number: 211110-63-3
• Molecular Weight: 328.40
• UNSPSC 코드: 51111800
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 10 mg/mL, clear
• 저장 온도: −20°C
• SMILES string: O(CC(=O)O)c1cc(c(c(c1)C)Cc2cc(c(cc2)O)C(C)C)C
• InChI: 1S/C20H24O4/c1-12(2)17-9-15(5-6-19(17)21)10-18-13(3)7-16(8-14(18)4)24-11-20(22)23/h5-9,12,21H,10-11H2,1-4H3,(H,22,23)
• InChI key: QNAZTOHXCZPOSA-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Sobetirome is also termed as 2-(4-(4-(benzyloxy)-3-isopropylbenzyl)-3,5-dimethylphenoxy)acetic acid/ GC-1. It has an inner-ring and negatively charged carboxylate groups at physiological pH. Sobetirome is considered as a cholesterol lowering agent in humans.

Sobetirome is an orally active and potent agonist at thyroid hormone receptor (TR) β and TRα that displays selective tissue action. Sobetirome is devoid of thyrotoxic adverse effects on the heart, bone, and skeletal muscle.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3