SML2980

G6PDi-1

≥98% (HPLC)

• 동의어(들): 4-([5-oxo-6H,7H,8H,9H-cyclohepta[d]pyrimidin-2-yl]amino)thiophene-2-carbonitrile
• 실험식(Hill 표기법): C₁₄H₁₂N₄OS
• CAS Number: 2457232-14-1
• Molecular Weight: 284.34
• MDL number: MFCD32899271
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: N#CC1=CC(NC2=NC=C3C(CCCCC3=N2)=O)=CS1
• InChI: 1S/C14H12N4OS/c15-6-10-5-9(8-20-10)17-14-16-7-11-12(18-14)3-1-2-4-13(11)19/h5,7-8H,1-4H2,(H,16,17,18)
• InChI key: USWCHVCZOGGQQA-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

G6PDi-1 is a cell penetrant potent and selective nonsteroidal inhibitor of glucose-6-phosphate dehydrogenase (G6PD). G6PDi-1 strongly depletes NADPH in lymphocytes. It decreases inflammatory cytokine response in macrophages, and suppresses respiratory burst in neutrophils.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable