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Merck
모든 사진(1)

주요 문서

SML3514

Sigma-Aldrich

Corylin

≥98% (HPLC)

동의어(들):

3-(2,2-Dimethyl-2H-1-benzopyran-6-yl)-7-hydroxy-4H-1-benzopyran-4-one

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About This Item

실험식(Hill 표기법):
C20H16O4
CAS Number:
Molecular Weight:
320.34
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.77

Quality Level

분석

≥98% (HPLC)

형태

powder

색상

white to beige

solubility

DMSO: 2 mg/mL, clear

저장 온도

2-8°C

SMILES string

O=C1C2=CC=C(C=C2OC=C1C3=CC4=C(C=C3)OC(C)(C)C=C4)O

생화학적/생리학적 작용

Corylin is a flavonoid isolated from fruit and seed of medical herb Psoralea corylifolia that extend the replicative lifespan in yeast by targeting the Gtr1 protein. Also, Corylin extends lifespan in mice fed a high-fat diet. Corylin exhibits numerous pharmacological effects such as antioxidant properties, anti-inflammatory effects, osteoblastic proliferation-stimulating activity, insulin resistance amelioration.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

I-Chen Chen et al.
Pharmaceuticals (Basel, Switzerland), 14(10) (2021-10-24)
Acute lung injury (ALI) is a high mortality disease with acute inflammation. Corylin is a compound isolated from the whole plant of Psoralea corylifolia L. and has been reported to have anti-inflammatory activities. Herein, we investigated the therapeutic potential of
Zi-Yu Chang et al.
International journal of molecular sciences, 23(5) (2022-03-11)
Inflammatory bowel disease (IBD) involves chronic inflammation, loss of epithelial integrity, and gastrointestinal microbiota dysbiosis, resulting in the development of a colon cancer known as colitis-associated colorectal cancer (CAC). In this study, we evaluated the effects of corylin in a
Tong-Hong Wang et al.
Nature communications, 13(1), 1238-1238 (2022-03-11)
In the long history of traditional Chinese medicine, single herbs and complex formulas have been suggested to increase lifespan. However, the identification of single molecules responsible for lifespan extension has been challenging. Here, we collected a list of traditional Chinese

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