SML3663
CAY10499
≥98% (HPLC)
동의어(들):
Benzyl 4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-2-methylphenylcarbamate, CAY 10499, CAY-10499, LEI 103, LEI-103, LEI103, Phenylmethyl N-[4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-2-methylphenyl]carbamate, [4-(5-Methoxy-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-2-methylphenyl]-carbamic acid phenylmethyl ester
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C18H17N3O5
CAS Number:
Molecular Weight:
355.34
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.77
추천 제품
생화학적/생리학적 작용
CAY10499 is a potent inhibitor against fatty acid amide hydrolase, hormone-sensitive lipase, and monoglyceride lipase (FAAH/HSL/MGL(MAGL) IC50 = 86/90/92 nM). Note: CAY10499 is reported to be irreversible by Muccioli et al. (PMID 18855964) and reversible by Minkkila et al. (PMID 19472270). Reported IC50 values vary depending greatly on pre-incubation time, substrates, enzyme source, as well as other experimental parameters employed.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Orly Laufman et al.
Cell, 178(2), 275-289 (2019-06-18)
Positive-stranded RNA viruses extensively remodel host cell architecture to enable viral replication. Here, we examined the poorly understood formation of specialized membrane compartments that are critical sites for the synthesis of the viral genome. We show that the replication compartments
Screening of various hormone-sensitive lipase inhibitors as endocannabinoid-hydrolyzing enzyme inhibitors.
Anna Minkkilä et al.
ChemMedChem, 4(8), 1253-1259 (2009-05-28)
Giulio G Muccioli et al.
Chembiochem : a European journal of chemical biology, 9(16), 2704-2710 (2008-10-16)
Monoglyceride lipase (MGL) plays a major role in the metabolism of the lipid transmitter 2-arachidonoylglycerol (2-AG). This endocannabinoid is known to mediate a large number of physiological processes, and its regulation is thought to be of great therapeutic potential. However
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