MilliporeSigma
All Photos(1)

Documents

H2904

Sigma-Aldrich

HistoChoice® Tissue Fixative

All Photos(1)
NACRES:
NA.47

color

colorless

Quality Level

100

application(s)

hematology
histology

storage temp.

room temp

Related Categories

Application

Designed for the molecular biologist. Specially formulated to preserve antigenic sites for antibody probes and nucleic acid sites for in situ hybridizations. Fixed sections do not require predigestion or other recovery procedures to make important sites available.

Quality

Contains no formaldehyde, glutaraldehyde or mercury. Non-toxic

Legal Information

HistoChoice is a registered trademark of Amresco, Inc.

Pictograms

Exclamation markHealth hazard
GHS07,GHS08

Signal Word

Warning

Precautionary Statements

P280 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Inhalation - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (Example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 6

1 of 6

Formaldehyde solution 4%, buffered, pH 6.9 (approx. 10% Formalin solution) for histology

Sigma-Aldrich

1.00496

Formaldehyde solution 4%, buffered, pH 6.9

Sigma-Aldrich

Sigma-Aldrich

HT501320

Formalin solution, neutral buffered, 10%

Bouin’s solution

Sigma-Aldrich

HT10132

Bouin′s solution

Paraformaldehyde reagent grade, crystalline

Sigma-Aldrich

P6148

Paraformaldehyde

Hydrogen peroxide solution 30 % (w/w) in H2O, contains stabilizer

Sigma-Aldrich

H1009

Hydrogen peroxide solution

Methanol suitable for HPLC, ≥99.9%

Sigma-Aldrich

34860

Methanol

J Melrose et al.
Biotechnic & histochemistry : official publication of the Biological Stain Commission, 83(1), 47-53 (2008-06-24)
Histochoice is a proprietary nontoxic, non-cross-linking fixative designed by the manufacturer to replace formaldehyde based fixation protocols. We compared Histochoice and formalin fixation for several cartilaginous tissues including, articular and growth plate cartilage, meniscus and intervertebral disc. The tissues were
D G Vince et al.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology, 15(2), 119-129 (1997-01-01)
Formaldehyde fixatives have traditionally been used to preserve tissues as they impart excellent morphological preservation. Formaldehyde fixes tissue by cross linking, a process which can reduce the antigenicity of tissue and weakens the intensity of immunohistochemical stains. Preliminary studies have
M A Kacena et al.
Biotechnic & histochemistry : official publication of the Biological Stain Commission, 79(5-6), 185-190 (2005-03-15)
We compared histochemical and immunohistochemical staining as well as fluorochrome labeling in murine bone specimens that were fixed with 10% neutral buffered formalin to those fixed with HistoChoice. We showed that sections from undecalcified tibiae fixed for 4 h in
Michael E Titford et al.
Archives of pathology & laboratory medicine, 129(4), 502-506 (2005-03-30)
In 1987, the Formaldehyde Standard became law in the United States, alerting laboratory workers to the potential carcinogenicity of formaldehyde. As a result, a variety of proprietary fixatives were developed for use in surgical pathology. To assess histomorphology with different
Yan Levitsky et al.
International journal of molecular sciences, 21(11) (2020-06-03)
Mitochondrial damage in the cells comprising inner (retinal endothelial cells) and outer (retinal pigment epithelium (RPE)) blood-retinal barriers (BRB) is known to precede the initial BRB breakdown and further histopathological abnormalities in diabetic retinopathy (DR). We previously demonstrated that activation
View All Related Papers

Related Content

Preparation & Staining of 3D Printed Tissues & Scaffolds

Three-dimensional (3D) printing of biological tissue is rapidly becoming an integral part of tissue engineering.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service