177717

2,5-Dimethylfuran

99%

• Synonym(s): 2-Methyl-5-methylfuran
• Empirical Formula (Hill Notation): C₆H₈O
• CAS Number: 625-86-5
• Molecular Weight: 96.13
• Beilstein/REAXYS Number: 106449
• EC Number: 210-914-3
• MDL number: MFCD00003250
• UNSPSC Code: 12352100
• PubChem Substance ID: 24850381
• NACRES: NA.22

Properties

• vapor density: 3.31 (vs air)
• assay: 99%
• form: liquid
• refractive index: n20/D 1.441 (lit.)
• bp: 92-94 °C (lit.)
• mp: −62 °C (lit.)
• density: 0.903 g/mL at 25 °C (lit.)
• SMILES string: Cc1ccc(C)o1
• InChI: 1S/C6H8O/c1-5-3-4-6(2)7-5/h3-4H,1-2H3
• InChI key: GSNUFIFRDBKVIE-UHFFFAOYSA-N

Description

General description

2,5-Dimethylfuran is a heterocyclic furan used as a building block in organic synthesis.

Application

2,5-Dimethylfuran can be used as:

• A reactant to prepare exo-maleimide-dimethylfuran cyclo adduct, which is used in the synthesis of oligonucleotide conjugates.
• An arynophile to synthesize 1,4-dimethyl-1,4-dihydro-1,4-epoxynaphthalene (fused benzene) by reacting with a mixture of neopentyl glycol and 2-hydroxyphenylboronic acid in the presence of a strong base.
• A precursor to prepare p-xylene via Diels-Alder cycloaddition and subsequent dehydration reaction.

Safety Information

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H302,H315,H317,H319,H335
• pcodes: P210 - P233 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 33.8 °F
• flash_point_c: 1 °C
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter