MilliporeSigma
All Photos(3)

Documents

184489

Sigma-Aldrich

1,3-Dichloro-2-propanol

97%

Sign Into View Organizational & Contract Pricing

Synonym(s):
Glycerol-α,γ-dichlorohydrin
Linear Formula:
(ClCH2)2CHOH
CAS Number:
Molecular Weight:
128.99
Beilstein:
1732063
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

Assay

97%

form

liquid

refractive index

n20/D 1.483 (lit.)

bp

174.3 °C (lit.)

mp

−4 °C (lit.)

solubility

water: soluble 10 part
alcohol: miscible
diethyl ether: miscible

density

1.363 g/mL at 20 °C
1.351 g/mL at 25 °C (lit.)

SMILES string

OC(CCl)CCl

InChI

1S/C3H6Cl2O/c4-1-3(6)2-5/h3,6H,1-2H2

InChI key

DEWLEGDTCGBNGU-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
292087185744107271
1-Chloro-2-propanol 70%

Sigma-Aldrich

292087

1-Chloro-2-propanol

2-Chloroethanol 99%

Sigma-Aldrich

185744

2-Chloroethanol

form

liquid

form

-

form

liquid

form

-

refractive index

n20/D 1.483 (lit.)

refractive index

n20/D 1.439 (lit.)

refractive index

n20/D 1.441 (lit.)

refractive index

n20/D 1.480 (lit.)

bp

174.3 °C (lit.)

bp

126-127 °C (lit.)

bp

129 °C (lit.)

bp

213 °C (lit.)

mp

−4 °C (lit.)

mp

-

mp

−89 °C (lit.)

mp

-

solubility

water: soluble 10 part, alcohol: miscible, diethyl ether: miscible

solubility

-

solubility

alcohol: miscible, water: miscible

solubility

H2O: soluble, alcohol: soluble, diethyl ether: soluble

General description

1,3-Dichloro-2-propanol is a food processing contaminant. Biotransformation of 1,3-dichloro-2-propanol to epichlorohydrin by the whole cells of recombinant Escherichia coli via resin-based in situ product removal has been investigated.

1,3-Dichloro-2-propanol is used as a pharmaceutical intermediate and solvent for paints, lacquers, and epoxy resins.

Application

1,3-Dichloro-2-propanol can be used as a reactant to synthesize:
  • Hydroxyl-N-tosylcyclams via sodium ethoxide catalyzed cyclization reaction with di(poly)-N-tosylamides.
  • (R)-Epichlorohydrin using biocatalysts.
  • 1,3-dichloropropene, a soil fumigant, and synthetic glycerol.

It can also be used as an intermediate in the production of epoxy resins, as well as a solvent for hard resins and nitrocellulose.

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Carc. 1B

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

186.8 °F - closed cup

Flash Point(C)

86 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 3

1 of 3

(±)-Epichlorohydrin purum, ≥99% (GC)

Sigma-Aldrich

45340

(±)-Epichlorohydrin

(±)-Epichlorohydrin analytical standard

Supelco

02578

(±)-Epichlorohydrin

Soy-based adhesives with 1, 3-dichloro-2-propanol as a curing agent
Rogers J, et al.
Wood and Fiber Science, 36(2), 186-194 (2004)
Role of mitogen-activated protein kinases and nuclear factor-kappa B in 1, 3-dichloro-2-propanol-induced hepatic injury
Lee In-Chul, et al.
Laboratory Animal Research, 32(1), 24-33 (2016)
Direct preparation kinetics of 1, 3-dichloro-2-propanol from glycerol using acetic acid catalyst
Luo, Zheng-Hong and You, et al.
Industrial & Engineering Chemistry Research, 48, 446-452 (2009)
A Practical Synthesis of Hydroxyl-N-tosylcyclams via Cyclization of 1, 3-Dichloro-2-propanol with Disodium Di (Poly)-N-Tosylamides
Wu Minghu, et al.
Synthetic Communications, 25(9), 1427-1431 (1995)
A rapid and sensitive GC--MS method for determination of 1, 3-dichloro-2-propanol in water
Schuhmacher, Rainer and Nurmi-Legat, et al.
Analytical and Bioanalytical Chemistry, 382, 366-371 (2005)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service