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Sigma-Aldrich

2,3-Dichloro-1-propanol

≥97.0% (GC)

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Synonym(s):
Glycerol-α,β-dichlorohydrin
Linear Formula:
ClCH2CHClCH2OH
CAS Number:
Molecular Weight:
128.99
Beilstein:
1732060
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥97.0% (GC)

density

1.360 g/mL at 20 °C (lit.)

SMILES string

OCC(Cl)CCl

InChI

1S/C3H6Cl2O/c4-1-3(5)2-6/h3,6H,1-2H2

InChI key

ZXCYIJGIGSDJQQ-UHFFFAOYSA-N

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1 of 4

This Item
292087184489189316
1-Chloro-2-propanol 70%

Sigma-Aldrich

292087

1-Chloro-2-propanol

density

1.360 g/mL at 20 °C (lit.)

density

1.111 g/mL at 25 °C (lit.)

density

1.363 g/mL at 20 °C, 1.351 g/mL at 25 °C (lit.)

density

-

General description

2,3-Dichloro-1-propanol belongs to the group of chloropropanols. Inhibitory effects of 2,3-dichloro-1-propanol on T cell both in vivo and in vitro is reported. Improved enantioselective resolution of (R,S)-2,3-dichloro-1-propanol to (S)-2, 3-dichloro-1-propanol by whole cells of a recombinant Escherichia coli in n-heptane-aqueous biphasic system is reported.

Application

2,3-Dichloro-1-propanol may be employed as carbon and energy supplement for the growth of Pseudomonas putida strain (MC4).

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 3 Oral - Eye Irrit. 2

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

199.4 °F

Flash Point(C)

93 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Jing Lu et al.
International immunopharmacology, 17(2), 321-328 (2013-07-16)
2,3-Dichloro-1-propanol (2,3-DCP) is a member of a group of chemicals known as chloropropanols. Currently, immunotoxicity of 2,3-DCP has not been reported. In the present study, we studied its inhibitory effects on T cell both in vivo and in vitro. The
K Fujishiro et al.
Fukuoka igaku zasshi = Hukuoka acta medica, 85(8), 247-250 (1994-08-01)
The toxicity of dichloropropanols (DCPs) was investigated by hematological and blood chemical examination. Solutions of two isomers of DCPs, 1,3-dichloro-2-propanol (DC2P) and 2,3-dichloro-1-propanol (DC1P) were dissolved in saline at a concentration of 100 mg/ml and 0.1 ml of each was
Muhammad Irfan Arif et al.
Applied and environmental microbiology, 78(17), 6128-6136 (2012-07-04)
A Pseudomonas putida strain (MC4) that can utilize 2,3-dichloro-1-propanol (DCP) and several aliphatic haloacids and haloalcohols as sole carbon and energy source for growth was isolated from contaminated soil. Degradation of DCP was found to start with oxidation and concomitant
A J Effendi et al.
Applied and environmental microbiology, 66(7), 2882-2887 (2000-07-06)
2,3-Dichloro-1-propanol is more chemically stable than its isomer, 1, 3-dichloro-2-propanol, and is therefore more difficult to degrade. The isolation of bacteria capable of complete mineralization of 2, 3-dichloro-1-propanol was successful only from enrichments at high pH. The bacteria thus isolated
Comparative testicular toxicities of two isomers of dichloropropanol, 2,3-dichloro-1-propanol, and 1,3-dichloro-2-propanol, and their metabolites alpha-chlorohydrin and epichlorohydrin, and the potent testicular toxicant 1,2-dibromo-3-chloropropane.
M Omura et al.
Bulletin of environmental contamination and toxicology, 55(1), 1-7 (1995-07-01)

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