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240230

Sigma-Aldrich

Phthalimide

≥99%

Synonym(s):

1,3-Dihydro-1,3-dioxoisoindole

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About This Item

Empirical Formula (Hill Notation):
C8H5NO2
CAS Number:
85-41-6
Molecular Weight:
147.13
Beilstein/REAXYS Number:
118522
EC Number:
201-603-3
MDL number:
MFCD00005881
UNSPSC Code:
12352100
PubChem Substance ID:
24854410
NACRES:
NA.22

assay

≥99%

mp

232-235 °C (lit.)

solubility

water: slightly soluble(lit.)

SMILES string

O=C1NC(=O)c2ccccc12

InChI

1S/C8H5NO2/c10-7-5-3-1-2-4-6(5)8(11)9-7/h1-4H,(H,9,10,11)

InChI key

XKJCHHZQLQNZHY-UHFFFAOYSA-N

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Application

Phthalimide was used in the synthesis of 6-amino agarose (AA) by Mitsunobu-inspired microwave mediated method.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

302.0 °F - closed cup

flash_point_c

150 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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N-Bromophthalimide 95%

Sigma-Aldrich

260908

N-Bromophthalimide

N-(4-Bromobutyl)phthalimide 98%

Sigma-Aldrich

100919

N-(4-Bromobutyl)phthalimide

Alessio Pierini et al.
Journal of veterinary science, 21(5), e60-e60 (2020-10-06)
Tumor-associated neoangiogenesis is a crucial target for antitumor therapies. Thalidomide (TAL) is a promising anti-neoangiogenetic drug that has recently been used in the treatment of several malignancies in dogs. The aim of the study was to assess the pharmacokinetics of
Stalin Kondaveeti et al.
Carbohydrate polymers, 106, 365-373 (2014-04-12)
A facile 6-aminoagarose (AA) mediated synthesis of new fluorogenic amides of agarose with nicotinic (AA-NA) and picolinic acids (AA-PA) employing carbodiimide chemistry have been described. 6-Amino agarose (AA) was synthesized in a facile Mitsunobu-inspired microwave mediated method involving the reaction
Stanton Hon Lung Kok et al.
Bioorganic & medicinal chemistry, 16(7), 3626-3631 (2008-02-26)
Phthalic anhydride is a highly toxic substance, facing, however, the problem of hydrolysis. In fact, it is rapidly hydrolyzed in aqueous medium, generating phthalic acid as the final product, which is almost harmless to viable cells. Here we describe the
Kazuaki Ishihara et al.
Organic letters, 10(13), 2893-2896 (2008-06-07)
Catalytic and highly enantioselective Diels-Alder reaction of cyclic and acyclic dienes with alpha-phthalimidoacroleins provides cyclic alpha-quaternary alpha-amino acid precursors. The conformationally flexible chiral ammonium salt of H-L-Phe-L-Leu-N(CH(2)CH(2)) 2-reduced triamine with pentafluorobenzensulfonic acid is very effective as an asymmetric catalyst for
Abhishek A Kantak et al.
Journal of the American Chemical Society, 133(49), 19960-19965 (2011-10-21)
The development of a novel intermolecular oxidative amination reaction, a synthetic transformation that involves the simultaneous functionalization of both a N-H and C-H bond, is described. The process, which is mediated by an I(III) oxidant and contains no metal catalysts
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