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329207

Sigma-Aldrich

Dianhydro-D-glucitol

98%

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Synonym(s):
1,4:3,6-Dianhydro-D-sorbitol, D-Isosorbide
Empirical Formula (Hill Notation):
C6H10O4
CAS Number:
Molecular Weight:
146.14
Beilstein/REAXYS Number:
80510
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

98%

form

solid

optical activity

[α]20/D +45.2°, c = 3 in H2O

mp

60-63 °C (lit.)

SMILES string

O[C@H]1CO[C@@H]2[C@H](O)CO[C@H]12

InChI

1S/C6H10O4/c7-3-1-9-6-4(8)2-10-5(3)6/h3-8H,1-2H2/t3-,4+,5-,6-/m1/s1

InChI key

KLDXJTOLSGUMSJ-JGWLITMVSA-N

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1 of 4

This Item
489182309532PHR2558
vibrant-m

329207

Dianhydro-D-glucitol

vibrant-m

489182

D-Sorbitol-1-13C

vibrant-m

309532

Sorbitol F solution

vibrant-m

PHR2558

1,4-Sorbitan

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

300

mp

60-63 °C (lit.)

mp

98-100 °C (lit.)

mp

-

mp

-

form

solid

form

solid

form

viscous liquid

form

solid

optical activity

[α]20/D +45.2°, c = 3 in H2O

optical activity

[α]25/D +101°, c = 0.5 in acidified ammonium molybdate

optical activity

-

optical activity

-

Application

Dianhydro-D-glucitol is a greener ingredient widely used as a monomer and building block for a variety of polymers and functional materials, for medical and pharmaceutical applications. It is also used as a fuel or fuel additive.
Applications include:
  • Preparation of renewable polyesters for coating applications.
  • Synthesis of isosorbide esters such as oligo(isosorbide adipate) (OSA), oligo(isosorbide suberate) (OSS), and isosorbide dihexanoate (SDH) as renewable alternatives to phthalate plasticizers.
  • Synthesis of biodegradable porous polyurethane scaffolds for tissue repair and regeneration.
  • Synthesis of the aspirin prodrug, isosorbide-2,5-diaspirinate (ISDA).

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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