341436

Tetramethyl orthosilicate

≥99%

• Synonym(s): Tetramethoxysilane
• Linear Formula: Si(OCH₃)₄
• CAS Number: 681-84-5
• Molecular Weight: 152.22
• Beilstein/REAXYS Number: 1699658
• EC Number: 211-656-4
• MDL number: MFCD00008341
• UNSPSC Code: 12352103
• PubChem Substance ID: 24860943
• NACRES: NA.23

Properties

• vapor density: 5.25 (vs air)
• Quality Level: 200
• vapor pressure: 13 hPa ( 20 °C)
• assay: ≥99%
• form: liquid
• refractive index: n20/D 1.368 (lit.)
• bp: 121-122 °C (lit.)
• mp: −4 °C (lit.)
• density: 1.023 g/mL at 25 °C (lit.)
• SMILES string: CO[Si](OC)(OC)OC
• InChI: 1S/C4H12O4Si/c1-5-9(6-2,7-3)8-4/h1-4H3
• InChI key: LFQCEHFDDXELDD-UHFFFAOYSA-N

Description

General description

Tetramethyl orthosilicate is a colorless organosilicon compound consisting of four methoxy groups bonded to a silicon atom. On hydrolysis, it produces silicon dioxide and methanol. It has been widely used in catalysis, synthesis of nanomaterials, ceramics, zeolites, and coating materials.

Application

Tetramethyl orthosilicate can be used:

• As a precursor to synthesize organic-inorganic coating materials by sol-gel processing method.
• As an efficient reagent for direct amidation of aliphatic and aromatic carboxylic acids with amines and anilines.
• As a precursor to fabricate SiO₂ nanocomposite films by chemical vapor deposition(CVD) method.
• As a selective catalyst ofC3-methylation of indole.

Used in the sol-gel synthesis of chromium-doped silicates and in the formation of hexagonal mesoporous silica layers.

Safety Information

• pictograms: GHS02,GHS06,GHS05
• signalword: Danger
• hcodes: H226,H315,H318,H330
• pcodes: P210 - P233 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Inhalation - Eye Dam. 1 - Flam. Liq. 3 - Skin Irrit. 2
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: 78.8 °F - closed cup
• flash_point_c: 26 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter