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481181

Sigma-Aldrich

Silver(I) sulfadiazine

98%

Synonym(s):

Silver sulfadiazine, Sulfadiazine silver

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About This Item

Empirical Formula (Hill Notation):
C10H9AgN4O2S
CAS Number:
22199-08-2
Molecular Weight:
357.14
EC Number:
244-834-5
MDL number:
MFCD00072101
UNSPSC Code:
12352302
PubChem Substance ID:
24871745
NACRES:
NA.23

Quality Level

100

assay

98%

form

powder

mp

285 °C (dec.) (lit.)

SMILES string

Nc1ccc(cc1)S(=O)(=O)N([Ag])c2ncccn2

InChI

1S/C10H9N4O2S.Ag/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1

InChI key

UEJSSZHHYBHCEL-UHFFFAOYSA-N

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Application

Silver(I) sulfadiazine (AgSD) is popularly used for treating second-degree burn wounds as it acts as an antimicrobial agent and prevents infections. Silver sulfadiazine-impregnated polyurethane (PU) foam, chitosan/chondroitin sulfate films may be used for wound dressing.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF3160V
WXBD9153V
MKCS0591
MKCN0160
MKCJ6788

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Daniel J Ostlie et al.
Journal of pediatric surgery, 47(6), 1204-1207 (2012-06-19)
The 2 most commonly used topical agents for partial thickness burns are silver sulfadiazine (SSD) and collagenase ointment (CO). Silver sulfadiazine holds antibacterial properties, and eschar separation occurs naturally. Collagenase ointment is an enzyme that cleaves denatured collagen facilitating separation
Annette Downe
British journal of community nursing, Suppl, S32-S32 (2013-05-21)
This product focus seeks to give an overview of the management of wound bioburden in relation to the use of antimicrobial dressings, according to recent guidelines and best practice statements. Identification of critical colonisation/localised infection and the role of biofilms
Luísiane de Ávila Santana et al.
Ultrasonics, 53(4), 870-879 (2013-01-09)
The immunological mechanisms that are triggered by Low-Intensity Pulsed Ultrasound (LIPUS) in wound healing are unknown. In the present study, experimental groups were used to assess the treatment of chronic venous ulcers with 30mW/cm(2) SATA peripheral LIPUS three times per
Silver as biocides in burn and wound dressings and bacterial resistance to silver compounds.
Silver S, et al.
Journal of Industrial Microbiology, 33(7), 627-634 (2006)
Silver sulfadiazine loaded chitosan/chondroitin sulfate films for a potential wound dressing application
Fajardo AR, et al.
Materials Science & Engineering. C, Materials For Biological Applications, 33(2), 588-595 (2013)
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