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484903

Sigma-Aldrich

Piperazine-2-carboxylic acid dihydrochloride

98%

Synonym(s):

(±)-Piperazine-2-carboxylic acid dihydrochloride

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About This Item

Empirical Formula (Hill Notation):
C5H10N2O2 · 2HCl
CAS Number:
3022-15-9
Molecular Weight:
203.07
MDL number:
MFCD00044803
UNSPSC Code:
12352100
PubChem Substance ID:
24871999
NACRES:
NA.22

assay

98%

mp

265 °C (dec.) (lit.)

SMILES string

Cl[H].Cl[H].OC(=O)C1CNCCN1

InChI

1S/C5H10N2O2.2ClH/c8-5(9)4-3-6-1-2-7-4;;/h4,6-7H,1-3H2,(H,8,9);2*1H

InChI key

WNSDZBQLMGKPQS-UHFFFAOYSA-N

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Poly-(amidoamine) (PAMAM) and poly-(propylenimine) (PPI) are the two most widely investigated dendrimers for drug and gene delivery. In order to enhance DNA transfection activity of these dendrimers, generation 3 and 4 PAMAM and generation 4 and 5 PPI were modified
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European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 96, 76-88 (2015-07-26)
Branched polyethylenimine (PEI) is extensively used as a polycationic non-viral vector for gene delivery. Polyplexes formed with PEI are believed to be released from endocytotic vesicles by the osmotic burst mechanism in the rate-limiting step in transfection. Increasing the buffering

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