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679437

Sigma-Aldrich

4-(Bromomethyl)phenylboronic acid

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Synonym(s):
α-Bromo-p-tolueneboronic acid, p-Boronobenzyl bromide
Linear Formula:
BrCH2(C6H4)B(OH)2
CAS Number:
Molecular Weight:
214.85
MDL number:
PubChem Substance ID:
NACRES:
NA.22

form

solid

Quality Level

mp

173-177 °C

storage temp.

2-8°C

SMILES string

OB(O)c1ccc(CBr)cc1

InChI

1S/C7H8BBrO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4,10-11H,5H2

InChI key

PDNOURKEZJZJNZ-UHFFFAOYSA-N

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This Item
679453715492679445
mp

173-177 °C

mp

158-162 °C

mp

141-145 °C

mp

224-228 °C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

General description

May contain varying amounts of anhydride

Application

Reactant involved in:
  • Design of boronic acid-based autotaxin inhibitors
  • Synthesis of boronated phosphonium salts
  • Studies of incorporation of boronic acid groups to enhance gene transfection capability
  • Investigations of the effect of boronic acid-positioning in optical glucose-sensing ensemble

Pictograms

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Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Journal of controlled release : official journal of the Controlled Release Society, 321, 159-173 (2020-02-12)
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MicroRNAs (miRNAs) therapy has shown to have great promise for the treatment of androgen-independent prostate cancer (AIPC) due to the low efficiency of hormonal therapy. However, instability of RNA and inefficiency of RNA therapy limit the use of miRNAs in
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Cationic dendrimers are widely used as nonviral gene vectors, however, current gene materials based on dendrimers are either little effective or too toxic on the transfected cells. Here, a facile strategy is presented to prepare high efficient dendrimers with low

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