745774

8-Amino-1-octanethiol hydrochloride

95%

• Synonym(s): 8-Mercaptooctylamine hydrochloride
• Empirical Formula (Hill Notation): C₈H₁₉NS · HCl
• CAS Number: 937706-44-0
• Molecular Weight: 197.77
• NACRES: NA.23
• PubChem Substance ID: 329765011
• UNSPSC Code: 12352103
• MDL number: MFCD28016329

Properties

• Quality Level: 100
• assay: 95%
• form: solid
• mp: 158-163 °C
• storage temp.: 2-8°C
• SMILES string: SCCCCCCCCN.Cl
• InChI: 1S/C8H19NS.ClH/c9-7-5-3-1-2-4-6-8-10;/h10H,1-9H2;1H
• InChI key: CCWZBRKMJBSNQS-UHFFFAOYSA-N

Description

General description

8-Amino-1-octanethiol hydrochloride (8-AOT) is an amine based alkanethiol that can be used as a self-assembled monolayer (SAM) on a variety of surfaces. It facilitates the immobilization of surface atoms and controls the physiochemical properties of the substrate.

Application

8-AOT can be used in the surface functionalization of gold electrodes for the trace analysis of oligonucleotide using poly nucleic acid (PNA) based ion-channel sensors. It can be used in the fabrication of peptide microarray for surface plasmon resonance based screening of protein kinase activity.

Self Assembly Molecules (SAMs); the amino group is usually modified using amine-reactive materials; such as proteins or biomaterials; to functionalize the gold surface. It is used for biosenors with large amounts of immobilized protein and suppression of nonspecific adsorption

Safety Information

• pictograms: GHS09
• signalword: Warning
• hcodes: H410
• pcodes: P273 - P391 - P501
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable