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MilliporeSigma

86778

Sigma-Aldrich

3′,3″,5′,5″-Tetrabromophenolphthalein ethyl ester

for microscopy

Synonym(s):

TBPE

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About This Item

Empirical Formula (Hill Notation):
C22H14Br4O4
CAS Number:
Molecular Weight:
661.96
Beilstein/REAXYS Number:
2228548
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

grade

for microscopy

Quality Level

form

solid

SMILES string

CCOC(=O)c1ccccc1\C(c2cc(Br)c(O)c(Br)c2)=C3\C=C(Br)C(=O)C(Br)=C3

InChI

1S/C22H14Br4O4/c1-2-30-22(29)14-6-4-3-5-13(14)19(11-7-15(23)20(27)16(24)8-11)12-9-17(25)21(28)18(26)10-12/h3-10,27H,2H2,1H3

InChI key

SQFXATUXPUCFFO-UHFFFAOYSA-N

Application

3′,3″,5′,5″-Tetrabromophenolphthalein ethyl ester (TBPE) is an anionic dye used as a counter ion in the spectrophotometric determination of cationic surfactants.[1] TBPE is also used in the spectrometric determination of aliphatic primary, secondary and tertiary amines.[2]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Simple method for spectrophotometric determination of cationic surfactants without liquid-liquid extraction.
Kamaya M, et al.
Analytica Chimica Acta, 384(2), 215-218 (1999)
Simultaneous spectrophotometric analysis of aliphatic amines utilizing thermochromism of charge-transfer complexes with tetrabromophenolphthalein ethyl ester.
Sakai T, et al.
Analytical Sciences, 21(12), 1557-1560 (2005)
[Application of tetrabromophenolphthalein ethyl ester (TBPE) indicator-dye to pharmaco-analysis].
G Szász et al.
Acta pharmaceutica Hungarica, 51(1), 43-47 (1981-01-01)
Ion association titration for the determination of local anesthetics in pharmaceuticals with tetrabromophenolphthalein ethyl ester as an indicator.
T Sakai et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 17(9), 1105-1107 (2001-11-16)
J G Rio et al.
Journal of analytical toxicology, 5(6), 267-269 (1981-11-01)
A simple direct colorimetric test using a tetrabromophenolphthalein reagent for detecting basic drugs in urine is described. The response of 62 commonly encountered drugs and metabolites to this test are described and 39 of these compounds were found to react.

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