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900926

Sigma-Aldrich

Branched PEI-g-PEG

PEG Mn 550

Synonym(s):

Branched polyethylenimine-graft-poly(ethylene glycol), PEI-g-PEG, PEI-PEG

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About This Item

Linear Formula:
H3CO[(CH2)2O]nC12H23N3O3[NH(CH2)2]mNH2
UNSPSC Code:
12162002
NACRES:
NA.23

form

liquid

Quality Level

100

mol wt

PEG Mn 550

storage temp.

2-8°C

Application

Branched PEI-g-PEG, PEG Mn 550 was derived from Sigma-Aldrich Product 408727. Based upon an approximate Mw of 25,000 for the branched PEI, Product 900926 contains approximately 55 grafted PEG chains per PEI unit (by NMR).

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

>230.0 °F

flash_point_c

> 110 °C

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Certificates of Analysis (COA)

Lot/Batch Number
MKCT2990
MKCF0802

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Katharina Ladewig et al.
Journal of biomedical materials research. Part A, 102(7), 2137-2146 (2013-07-31)
High molecular weight (MW) polyethyleneimine (PEI) has been successfully used for the transfection of a broad variety of cell lines. In contrast to low MW PEI, which exhibits low transfection efficiencies but also low cytotoxicity, high MW PEI-mediated transfection achieves
Jing Wang et al.
Biomaterials science, 4(9), 1351-1360 (2016-07-19)
Zwitterionic poly(carboxybetaine) (PCB), poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) and non-ionic poly(ethylene glycol) (PEG), which have similar degrees of polymerization, were grafted to branched polyethyleneimine (PEI) to generate PCB-grafted PEI (PEI-PCB), PMPC-grafted PEI (PEI-PMPC) and PEG-grafted PEI (PEI-PEG) copolymers, respectively. These grafted PEI
Chunxi Liu et al.
Biomaterials, 34(10), 2547-2564 (2013-01-22)
Co-delivery of nucleic acids and chemotherapeutics has a potential to efficaciously treat human diseases via their synergetic effects. Activable therapeutic tools at the nanoscale are suitable platforms for combination therapy. In this study, we have developed a multifunctional nanoscaled delivery

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