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901594

Sigma-Aldrich

Diisopropylcarbodiimide solution

1 M in THF

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Synonym(s):
Diisopropylmethanediimine
Linear Formula:
C7H14N2
CAS Number:
MDL number:

form

liquid

reaction suitability

reaction type: Coupling Reactions

concentration

1 M in THF

density

0.870 g/mL

application(s)

peptide synthesis

InChI

1S/C7H14N2/c1-6(2)8-5-9-7(3)4/h6-7H,1-4H3

InChI key

BDNKZNFMNDZQMI-UHFFFAOYSA-N

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1 of 4

This Item
G152247608680303
Diisopropylcarbodiimide solution 1 M in THF

901594

Diisopropylcarbodiimide solution

Gentamicin solution Hybri-Max™, 0.1 μm filtered, 50 mg/mL gentamicin, BioReagent, suitable for hybridoma

G1522

Gentamicin solution

Formaldehyde solution for molecular biology, BioReagent, ≥36.0% in H2O (T)

47608

Formaldehyde solution

Tetrahydrofuran solution contains 20 % (v/v) 1,2-Propanediol

680303

Tetrahydrofuran solution

reaction suitability

reaction type: Coupling Reactions

reaction suitability

-

reaction suitability

-

reaction suitability

-

concentration

1 M in THF

concentration

50 mg/mL gentamicin

concentration

≥36.0% in H2O (T), 36.0-38.0% (aldehyde method)

concentration

-

density

0.870 g/mL

density

1.000 g/cm3

density

1.09 g/mL at 20 °C, 1.09 g/mL at 25 °C (lit.)

density

0.914 g/mL at 25 °C

application(s)

peptide synthesis

application(s)

-

application(s)

-

application(s)

-

Application

Coupling reagent for peptide syntheses.
DIC (N,N′-Diisopropylcarbodiimide) has been used in combination with 1-hydroxy-7-azabenzotriazole (HOAt) for the coupling of amino acid with N-allylglycine to form N-allylpeptide.
Valuable reagent offered as a solution in tetrahydrofuran for more convenient handling.

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Product No.
Description
Pricing

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Resp. Sens. 1 - Skin Sens. 1

supp_hazards

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

2.0 °F

flash_point_c

-16.66 °C


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Collection of Czechoslovak Chemical Communications, 59, 691-691 (1994)
Tetrahedron Letters, 35, 5981-5981 (1994)
Stéphane Chantepie et al.
PloS one, 10(7), e0133140-e0133140 (2015-07-29)
Do all traits within an organism age for the same reason? Evolutionary theories of aging share a common assumption: the strength of natural selection declines with age. A corollary is that additive genetic variance should increase with age. However, not
Cody L Gilleland et al.
Genetics, 201(1), 39-46 (2015-07-15)
A major goal in the study of human diseases is to assign functions to genes or genetic variants. The model organism Caenorhabditis elegans provides a powerful tool because homologs of many human genes are identifiable, and large collections of genetic
Tianyi Zhang et al.
Journal of cell science, 128(15), 2938-2950 (2015-06-21)
The v-ATPase is a fundamental eukaryotic enzyme that is central to cellular homeostasis. Although its impact on key metabolic regulators such as TORC1 is well documented, our knowledge of mechanisms that regulate v-ATPase activity is limited. Here, we report that

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