902071

Carboxylic acid poly(ethylene glycol)-block-poly(lactide-co-glycolide)

PEG average M_n 5000, PLGA average M_n 15000, lactide:glycolide (50:50)

• Synonym(s): Carboxylic acid-PEG-b-PLGA, Carboxylic acid-PEG-PLGA
• Linear Formula: C₆H₁₁O₃S(C₂H₄O)_nC₂H₄O[(C₂H₂O₂)x(C₃H₄O₂)_y]_mH
• UNSPSC Code: 12352106
• NACRES: NA.23

Properties

• description: Identity: Conforms to structure (by NMR)
• form: powder
• feed ratio: lactide:glycolide (50:50); lactide:glycolide:5 (50:50(by NMR))
• mol wt: PEG M_n 4000-7000 g/mol (by NMR); PEG average M_n 5000; PLGA M_n 13000-18000 g/mol (by NMR); PLGA average M_n 15000
• color: white
• storage temp.: −20°C

Description

Application

Carboxylic acid poly(ethylene glycol)-block-poly(lactide-co-glycolide) is a carboxylic acid-functionalized, biocompatible, amphiphilic block copolymer. Due to its self-assembling properties, this material can be used in the formation of nanoparticles for drug delivery. Additionally, due to the carboxylic acid-functionalization of the PEG block, this material can be used to rapidly covalently conjugate biomolecules, API, or targeting ligands. Potential uses include the targeted and/or controlled release of cancer drugs, anti-inflammatory drugs, antibiotics, or anesthetic agents.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable