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921610

Sigma-Aldrich

TissueFab® bioink 

(GelAlg)ma -Vis/405 nm

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Synonym(s):
Alginate, Alginate bioink, Alginate methacrylamide, Alginate methacrylate, Alginate methacryloyl, Bioink, Sodium alginate

Quality Level

description

suitable for 3D bioprinting applications

sterility

sterile-filtered

form

viscous liquid (or gel)

impurities

≤5 CFU/g Bioburden (Fungal)
≤5 CFU/g Bioburden (Total Aerobic)

color

colorless to pale yellow

particle size

0.2 μm

mp

6.5-7.5

application(s)

3D bioprinting

storage temp.

2-8°C

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Application

TissueFab® - AlgMA-UV bioink is an alginate methacrylate based bioink for 3D bioprinting applications. The formulation is optimized for 3D bioprinting of tissues and constructs using extrusion based 3D bioprinters. The bioink can be can be used to bioprint cell-laden hydrogels in your desired shape without any supporting material. The crosslinking of printed structures can be done in a single step using visible light mediated photocrosslinking. This bioink has applications in 3D cell culture, tissue engineering, and regenerative medicine.

This bioink is derived from natural polymers - alginate and gelatin. Alginate also known as sodium alginate or alginic acid, is a natural biopolymer obtained from brown algae. Alginate is a natural polysaccharide widely used in tissue engineering. Gelatin contains bioactive peptide sequences similar to native extracellular matrix which promotes integrin mediated cell adhesion and MMP sensitive enzymatic degradation which are essential for cellular functions such as migration, proliferation and differentiation.

Packaging

10 mL in glass bottle

Other Notes

  • Ready-to-use formulation optimized for high printing fidelity and cell viability, eliminating the lengthy bioink formulation development process
  • Includes step-by-step protocols
  • Suitable for different extrusion-based 3D bioprinter instruments

Legal Information

TISSUEFAB is a registered trademark of Sigma-Aldrich Co. LLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 3


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Articles

3D Bioprinting: Bioink Selection Guide

Bioinks can be 3D bioprinted into functional tissue constructs for drug screening, disease modeling, and in vitro transplantation. Choose the Bioinks and method for specific tissues engineering applications.

Recent Advances in 3D-Bioprinting-based Drug Screening

Learn how 3D bioprinting is revolutionizing drug discovery with highly-controllable cell co-culture, printable biomaterials, and its potential to simulate tissues and organs. This review paper also compares 3D bioprinting to other advanced biomimetic techniques such as organoids and organ chips.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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