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Poly (ethylene glycol)-block-Poly (sulfobetaine methacrylate)

PEG average Mn 5000, PSBMA Mn 13,000

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PEG-PDMAPS, PEG-PSBMA, PSBMA, Poly (sulfobetaine methacrylate)
Linear Formula:

mol wt

PEG average Mn 5000
PSBMA Mn 13,000

Quality Level

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Biocompatible, non-fouling block copolymer composed of a neutral PEG block and a zwitterionic poly(sulfobetaine methacrylate) (PSBMA) block.

Poly(sulfobetaine methacrylate) (PSBMA) is a well-known zwitterionic polymer, it is non-toxic and biocompatible. On each of its repeating unit, it carries both a positive charge and a negative charge, leading to its strong hydration capacity.

Surfaces coated with PSBMA showed super hydrophilic property and strong resistance to protein adsorption/bacterial adhesion, making this polymer a promising material in anti-fouling applications.

Storage Class

11 - Combustible Solids




Not applicable


Not applicable

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Jiang Wu et al.
Acta biomaterialia, 40, 172-181 (2016-05-05)
Nonfouling materials such as neutral poly(ethylene glycol) (PEG) and zwitterionic poly(sulfobetaine methacrylate) (pSBMA) are ideal biocompatible materials for drug, especially protein drug delivery. The interaction behavior of protein between the nonfouling materials could cause great impact on their future applications
Se Yeong Lee et al.
Biomaterials research, 22, 3-3 (2018-02-17)
Zwitterionic molecules have been widely studied as coating materials for preparing anti-fouling surfaces because they possess strong hydration properties that can resist non-specific protein adsorption. Numerous studies on surface modification using zwitterionic molecules have been investigated, such as electrochemically mediated

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