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Key Documents

L070150

Sigma-Aldrich

Fast Deprotection Cap 2

45-55 g/L (TAC2O content, gravimetric)

Synonym(s):

Fast Deprotection Cap A

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About This Item

UNSPSC Code:
12352106
NACRES:
NA.21

type

for DNA synthesis
for DNA synthesis

product line

Proligo Reagents

form

liquid

storage condition

dry at room temperature

concentration

45-55 g/L (TAC2O content, gravimetric)

technique(s)

DNA synthesis: suitable

color

clear

storage temp.

room temp

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General description

Fast Deprotection Cap 2 is an acetonitrile-based liquid reagent. It has a composition of Acetonitrile / TAC2O 100/5 (v/w).

Preparation Note

Acetonitrile / TAC2O 100/5 (v/w)

Other Notes

Fast Deprotection Cap A solution must be used for synthesis with Sigma-Aldrich′s TAC-protected phosphoramidites. Fast Deprotection Cap A solution, containing tert-butylphenoxyacetyl acetic anhydride (TAC2O) in acetonitrile, is used in place of Cap A solution to ensure that the displacement of tert-butylphenoxyacetyl (TAC) on guanine bases of the TAC-protected DNA and RNA phosphoramidites does not occur.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

35.6 °F - (Acetonitrile)

flash_point_c

2.0 °C - (Acetonitrile)

Certificates of Analysis (COA)

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