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Key Documents

L070000

Sigma-Aldrich

Fast Deprotection Cap A

45-55 g/L (TAC2O content, gravimetric)

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About This Item

UNSPSC Code:
41116105
NACRES:
NA.21

type

for DNA synthesis
for DNA synthesis

product line

Proligo Reagents

form

liquid

storage condition

dry at room temperature

concentration

45-55 g/L (TAC2O content, gravimetric)

color

clear

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General description

Fast Deprotection Cap A contains tert-butylphenoxyacetyl aceticanhydride (TAC2O) in tetrahydrofuran, which ensures thedisplacement of tert-butylphenoxyacetyl (TAC) on guanine bases doesnot occur.

Preparation Note

Tetrahydrofurane / TAC2O 100/5 (v/w)

Other Notes

Fast Deprotection Cap A solution must be used for synthesis with Sigma-Aldrich′s TAC-protected phosphoramidites. Fast Deprotection Cap A solution, containing tert-butylphenoxyacetyl acetic anhydride (TAC2O) in tetrahydrofuran, is used in place of Cap A solution to ensure that the displacement of tert-butylphenoxyacetyl (TAC) on guanine bases of the TAC-protected DNA and RNA phosphoramidites does not occur.

signalword

Danger

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system, Respiratory system

supp_hazards

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

6.1 °F

flash_point_c

-14.4 °C


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