Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

M072000

Sigma-Aldrich

2-Cyanoethyl N,N-diisopropylchlorophosphoramidite

Synonym(s):

Chloro(diisopropylamino)-β-cyanoethoxyphosphine

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
[(CH3)2CH]2NP(Cl)OCH2CH2CN
CAS Number:
Molecular Weight:
236.68
Beilstein/REAXYS Number:
3588525
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

type

for DNA synthesis

product line

Proligo Reagents

assay

≥97.0% (31P-NMR)

form

liquid

color

clear to very slightly hazy colorless

density

1.061 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CC(C)N(C(C)C)P(Cl)OCCC#N

InChI

1S/C9H18ClN2OP/c1-8(2)12(9(3)4)14(10)13-7-5-6-11/h8-9H,5,7H2,1-4H3

InChI key

QWTBDIBOOIAZEF-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

2-Cyanoethyl N,N-diisopropylchlorophosphoramidite is a monochloridite phosphorylation reagent used for DNA synthesis.

pictograms

FlameCorrosion

signalword

Danger

hcodes

Hazard Classifications

Pyr. Liq. 1 - Skin Corr. 1B

Storage Class

4.2 - Pyrophoric and self-heating hazardous materials

wgk_germany

WGK 3

flash_point_f

230.0 °F - closed cup

flash_point_c

110 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Abdelaziz Al Ouahabi et al.
Journal of the American Chemical Society, 137(16), 5629-5635 (2015-04-09)
Sequence-defined non-natural polyphosphates were prepared using iterative phosphoramidite protocols on a polystyrene solid support. Three monomers were used in this work: 2-cyanoethyl (3-dimethoxytrityloxy-propyl) diisopropylphosphoramidite (0), 2-cyanoethyl (3-dimethoxytrityloxy-2,2-dimethyl-propyl) diisopropylphosphoramidite (1), and 2-cyanoethyl (3-dimethoxytrityloxy-2,2-dipropargyl-propyl) diisopropylphosphoramidite (1'). Phosphoramidite coupling steps allowed rapid synthesis

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service