QBD10784

Biotin-dPEG^®₁₁-azide

• Synonym(s): Polyethylene glycol, alpha-(2-azidoethyl)-omega-[2-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]-poly(oxy-1,2-ethanediyl)
• Empirical Formula (Hill Notation): C₃₄H₆₄N₆O₁₃S
• CAS Number: 956494-20-5
• Molecular Weight: 796.97
• UNSPSC Code: 12352125
• PubChem Substance ID: 329823949
• NACRES: NA.22

Properties

• assay: >90%
• form: solid or viscous liquid
• reaction suitability: reaction type: Biotinylations; reagent type: cross-linking reagent
• polymer architecture: shape: linear; functionality: monofunctional
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: O=C1NC(C2N1)CSC2CCCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O

Description

Features and Benefits

Biotin-dPEG^®₁₁-azide is a single molecular weight dPEG^® that permits biotin labeling with precise spacing to molecules containing an alkyne using well-known, highly popular click chemistry. By inserting an alkyne function into the target molecule, site specific labeling can occur using either copper(I) catalyzed or strain-catalyzed click chemistry. The single molecular weight nature of the dPEG^® spacer (50.4 Å) allows the user to precisely tailor the distance between the biotin and the target molecule in order to receive optimal binding between biotin and avidin.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable