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QBD10819

Sigma-Aldrich

MAL-dPEG®11-Lipoamide

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Synonym(s):
Polyethylene glycol
Empirical Formula (Hill Notation):
C39H69N3O15S2
CAS Number:
Molecular Weight:
884.11
MDL number:
PubChem Substance ID:
NACRES:
NA.22

assay

>90%

form

solid or viscous liquid

reaction suitability

reagent type: chemical modification reagent
reagent type: cross-linking reagent
reactivity: gold reactive

polymer architecture

shape: linear
functionality: heterobifunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

O=C(CCCCC1SSCC1)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN2C(C=CC2=O)=O)=O

Features and Benefits

MAL-dPEG®11-lipoamide is a crosslinker designed to allow crosslinking of a sulfhydryl-containing molecule with a metal surface such as gold or silver. The hydrophilic, non-immunogenic, single molecular weight dPEG® spacer is 59.3 Å long, providing good separation between the target molecule and the metal surface. The spacer also increases the hydrodynamic volume of the conjugate and improves its water solubility. The maleimide function forms a thioether bond with a sulfhydryl group. One possible application of this product is immobilization of an antibody or antibody fragment onto a metal surface. Peptides and small molecules with free sulfhydryl groups could also be used in this way.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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