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MilliporeSigma

W355690

Sigma-Aldrich

Isopropyl myristate

≥98%

Synonym(s):

Isopropyl tetradecanoate, Myristic acid isopropyl ester

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100 μL
$305.10

$305.10

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100 μL
$305.10

About This Item

Linear Formula:
CH3(CH2)12COOCH(CH3)2
CAS Number:
Molecular Weight:
270.45
FEMA Number:
3556
Beilstein/REAXYS Number:
1781127
EC Number:
Council of Europe no.:
386
MDL number:
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
9.105
NACRES:
NA.21

$305.10

List Price$339.00Save 10%

Availability

Available to ship onJanuary 09, 2025Details


Request a Bulk OrderRequest more information

biological source

synthetic

Quality Level

grade

Fragrance grade
Halal
Kosher

agency

follows IFRA guidelines

reg. compliance

EU Regulation 1223/2009

assay

≥98%

refractive index

n20/D 1.434 (lit.)

bp

193 °C/20 mmHg (lit.)

mp

~3 °C (lit.)

density

0.85 g/mL at 25 °C (lit.)

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B8806A809717783
Calcein-AM suitable for fluorescence, BioReagent, ≥90% (HPLC)

17783

Calcein-AM

concentration

4 mM in DMSO

concentration

1 mg/mL in DMSO

concentration

10 mg/mL in H2O

concentration

-

color

colorless, white to off-white

color

colorless to yellow

color

orange to red

color

-

form

solution

form

liquid

form

solution

form

-

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

room temp

storage temp.

−20°C

General description

Isopropyl myristate is mainly used as a solubilizer, emulsifier and emollient in cosmetic and topical medicines. It is also used as a flavoring agent in the food industry.[1]

Application


  • Development of Nanostructured Lipid Carrier-Loaded Flavonoid-Enriched Zingiber officinale.: This research develops nanostructured lipid carriers for flavonoids derived from Zingiber officinale, employing Isopropyl myristate to stabilize these carriers and improve bioactive compound delivery (Shazwani SS et al., 2024).

  • Comparative evaluation of physical and chemical enhancement techniques for transdermal delivery of linagliptin.: The study compares various enhancement methods for transdermal drug delivery, including the use of Isopropyl myristate, highlighting its effectiveness in permeation enhancement techniques (Karve T et al., 2024).

  • Optimization of Conditions of Zanthoxylum Alkylamides Liposomes by Response Surface Methodology and the Absorption Characteristics of Liposomes in the Caco-2 Cell Monolayer Model.: This research optimizes liposome formulations containing Zanthoxylum alkylamides, with Isopropyl myristate being crucial in liposome stability and absorption characteristics (Wang R et al., 2024).

Biochem/physiol Actions

Odor at 1.0%
Taste at 10 ppm

Disclaimer

For R&D or non-EU Food use. Not for retail sale.

Storage Class

10 - Combustible liquids

wgk_germany

awg

flash_point_f

>302.0 °F

flash_point_c

> 150 °C

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Handbook of Preservatives, 425-425 (2004)
Ranajay Saha et al.
Langmuir : the ACS journal of surfaces and colloids, 28(22), 8309-8317 (2012-05-11)
An edible microemulsion (ME) composed of Tween 80/butyl lactate/isopropyl myristate (IPM)/water has been formulated. Pseudoternary phase diagram of the system contains a large single isotropic region. The phase behavior of the system is also studied at low pH (2.6) and
Qian Zhang et al.
Pharmaceutical research, 30(1), 32-40 (2012-08-28)
In principle, maximum transepidermal fluxes of solutes should be similar for different vehicles, except when the solute or vehicle modifies the skin. Here we estimated maximum flux, stratum corneum solubility, diffusivity and permeability coefficient for a range of similarly sized
Ji Zhang et al.
International journal of pharmaceutics, 421(1), 34-44 (2011-10-01)
In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant
Qingping Tian et al.
International journal of pharmaceutics, 426(1-2), 202-210 (2012-01-26)
To improve the skin permeation of naproxen with larger dosage, microemulsion with high content of naproxen was investigated for transdermal delivery and its solubilization mechanism was studied. Naproxen micoremulsions composed of 4% isopropyl myristate, 18% Tween 80, 18% ethanol and

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