W294004

Propylene glycol

≥99.5% (GC), FCC, FG

• Synonym(s): 1,2-Propanediol, Propylene glycol
• Linear Formula: CH₃CH(OH)CH₂OH
• CAS Number: 57-55-6
• Molecular Weight: 76.09
• FEMA Number: 2940
• Beilstein/REAXYS Number: 1340498
• EC Number: 200-338-0
• Council of Europe no.: 4212
• MDL number: MFCD00064272
• UNSPSC Code: 12164502
• PubChem Substance ID: 24901410
• NACRES: NA.21

Properties

• biological source: synthetic
• Quality Level: 400
• grade: FG; Fragrance grade; Halal; Kosher
• agency: follows IFRA guidelines
• reg. compliance: EU Regulation 1223/2009; EU Regulation 1334/2008 & 178/2002; FCC; FDA 21 CFR 175.300; FDA 21 CFR 175.320; FDA 21 CFR 176.180; FDA 21 CFR 176.210; FDA 21 CFR 184.1666
• vapor density: 2.62 (vs air)
• vapor pressure: 0.08 mmHg ( 20 °C)
• assay: ≥99.5% (GC)
• form: viscous liquid
• autoignition temp.: 779 °F
• expl. lim.: 12.5 %
• refractive index: n20/D 1.432 (lit.)
• bp: 187 °C (lit.)
• mp: −60 °C (lit.)
• density: 1.036 g/mL at 25 °C (lit.)
• application(s): flavors and fragrances
• documentation: see Safety & Documentation for available documents
• food allergen: no known allergens
• fragrance allergen: no known allergens
• organoleptic: odorless
• SMILES string: CC(O)CO
• InChI: 1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3
• InChI key: DNIAPMSPPWPWGF-UHFFFAOYSA-N

Description

General description

Propylene glycol is an aliphatic dihydric alcohol with a wide range of applications in the food industry such as an anticaking agent, antioxidant, humectant, flavoring agent, emulsifier, stabilizer, thickener etc.

Application

• Fatally impaired glucose digestion by propylene glycol in Aedes aegypti (Diptera: Culicidae) and co-formulation with terpenoids for enhancing attractive toxic sugar baits.: This study explores the application of propylene glycol in impairing glucose digestion in mosquitoes, offering a novel approach to vector control through enhanced toxic sugar baits. The synergy with terpenoids broadens its impact, marking significant progress in pest management strategies (Maes et al., 2024).


• Null cross-modal effects of olfactory training on visual, auditory or olfactory working memory in 6- to 9-year-old children.: This neuroscientific study utilizes propylene glycol in olfactory training exercises, investigating its potential to influence cross-modal sensory processing. Despite null findings, it provides a critical assessment of sensory integration therapies (Pieniak et al., 2024).


• Propylene glycol toxicity in an adolescent secondary to chronic cornstarch ingestion.: This medical case study addresses the risks associated with excessive propylene glycol intake, highlighting its potential toxic effects. The study serves as a crucial reminder of the need for regulatory scrutiny and public awareness regarding chemical additives in food products (Downey et al., 2024).

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 217.4 °F - closed cup
• flash_point_c: 103 °C - closed cup
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)