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134368

Sigma-Aldrich

1,2-Propanediol

ReagentPlus®, 99%

Synonym(s):

1,2-PDO, Propylene glycol

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About This Item

Linear Formula:
CH3CH(OH)CH2OH
CAS Number:
Molecular Weight:
76.09
Beilstein/REAXYS Number:
1340498
EC Number:
MDL number:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.21

vapor density

2.62 (vs air)

Quality Level

vapor pressure

0.08 mmHg ( 20 °C)

product line

ReagentPlus®

assay

99%

form

liquid

autoignition temp.

779 °F

expl. lim.

12.5 %

refractive index

n20/D 1.432 (lit.)

bp

187 °C (lit.)

mp

−60 °C (lit.)

density

1.036 g/mL at 25 °C (lit.)

SMILES string

CC(O)CO

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

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General description

1,2-Propanediol can be obtained as a byproduct in the dehydration of glycerol to hydroxyacetone.It can undergo condensation with sebacic acid and citric acid in the absence of catalyst to give poly((1,2-propanediol-sebacate)-citrate) (PPSC), an elastomeric polyester, which can find applications in tissue engineering and drug delivery.

Application

1,2-Propanediol has been used:
  • for removing excess Oil Red O stain in zebrafish larvae
  • in the preparation of alginate hydrogels
  • for the dissolution of androstenone
  • for the calibration of cone beam scanner in computed tomography

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

219.2 °F - closed cup

flash_point_c

104 °C - closed cup

ppe

Eyeshields, Gloves


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Selective hydrogenolysis of glycerol to 1, 2-propanediol: comparison of batch and continuous process operations
Rode.V.C, et al.
Organic Process Research & Development, 14, 1385-1392 (2010)
Synthesis, characterization and in vitro degradation of a novel degradable poly ((1, 2-propanediol-sebacate)-citrate) bio elastomer
Lie L, et al.
Polymer Degradation and Stability, 92, 389-396 (2007)
ZeGlobalTox: an innovative approach to address organ drug toxicity using zebrafish
Cornet C, et al.
International Journal of Molecular Sciences, 18(4), 864-864 (2017)
Prasanna R Karunanayaka et al.
Brain and behavior, 5(11), e00390-e00390 (2015-12-15)
The formation of an odor percept in humans is strongly associated with visual information. However, much less is known about the roles of learning and memory in shaping the multisensory nature of odor representations in the brain. The dynamics of
Male sexual orientation affects sensitivity to androstenone
Lubke K, et al.
Chemosensory Perception, 2(3), 154-160 (2009)

Protocols

Strat-M® synthetic membrane mimics the human skin for In-vitro permeation testing (IVPT) of topical and transdermal formulations

Chromatograms

suitable for GC

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